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Gene ontology
Version 2014-12-22
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Details for steroid hydroxylase activity
Gene ontology ID
GO:0008395
Definition
Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2
Synonyms
1. cytochrome P450 CYP2G1
2. olfactory-specific steroid hydroxylase activity
References
1. ISBN 0721662544
2. Reactome: R-HSA-191983 "Cholesterol is hydroxylated to 25-hydroxycholesterol"
3. Reactome: R-HSA-191999 "CYP27A1 27-hydroxylates 5bCHOL3a,7a,12a-triol"
4. Reactome: R-HSA-192042 "5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al"
5. Reactome: R-HSA-192054 "3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoate (THCA)"
6. Reactome: R-HSA-192123 "CYP27A1 27-hydroxylates CHOL"
7. Reactome: R-HSA-193060 "CYP19A1 hydroxylates ANDST to E1"
8. Reactome: R-HSA-193143 "CYP19A1 hydroxylates TEST to EST17b"
9. Reactome: R-HSA-193393 "5beta-cholestan-3alpha, 7alpha-diol is hydroxylated to 5beta-cholestan-3alpha, 7alpha, 26-triol"
10. Reactome: R-HSA-193460 "3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestanoate (DHCA)"
11. Reactome: R-HSA-193497 "5beta-cholestan-3alpha, 7alpha, 26-triol is oxidized to 3alpha, 7alpha-dihydroxy-5beta-cholestan-26-al"
12. Reactome: R-HSA-193713 "3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestanoate (TetraHCA)"
13. Reactome: R-HSA-193719 "5beta-cholestan-3alpha,7alpha,24(S),27-tetrol is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al"
14. Reactome: R-HSA-193737 "3alpha,7alpha,24(S)-trihydroxy-5beta-cholestan-27-al is oxidized to 3alpha,7alpha,24(S)-trihydroxy-5beta-cholestanoate (3,7,24THCA)"
15. Reactome: R-HSA-193780 "5beta-cholestan-3alpha,7alpha,12alpha,24(S),27-pentol is oxidized to 3alpha,7alpha,12alpha,24(S)-tetrahydroxy-5beta-cholestan-27-al"
16. Reactome: R-HSA-193787 "5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol is hydroxylated to 5beta-cholestan-3alpha,7alpha,12alpha,24(S), 27-pentol"
17. Reactome: R-HSA-193792 "CYP27A1 27-hydroxylates 5-CHOL3,7,24(s)-triol"
18. Reactome: R-HSA-193965 "CYP11B2 oxidises 18HCORST to ALDO"
19. Reactome: R-HSA-193995 "CYP11B2 18-hydroxylates CORST to 18HCORST"
20. Reactome: R-HSA-5601849 "Defective CYP19A1 does not convert ANDST to E1"
21. Reactome: R-HSA-5602170 "CYP27A1 does not 27-hydroxylate 5bCHOL3a,7a,12a-triol"
22. Reactome: R-HSA-6785244 "Defective CYP11B2 does not oxidise 18HCORST"
23. Reactome: R-HSA-6785245 "Defective CYP11B2 does not oxidise CORST"
24. Reactome: R-HSA-9035960 "Defective CYP27A1 does not 27-hydroxylate 5-CHOL3,7,24(s)-triol"
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