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Gene ontology
Version 2014-12-22
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Details for phosphoprotein phosphatase activity
3.1.3.16
Gene ontology ID
GO:0004721
Definition
Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity
Synonyms
1. phosphoprotein phosphohydrolase activity
2. protein phosphatase activity
3. protein phosphatase-1 activity
4. protein phosphatase-2A activity
5. protein phosphatase-2B activity
6. protein phosphatase-2C activity
References
1. EC 3.1.3.16
2. ISBN 0198547684
3. MetaCyc 3.1.3.16-RXN
4. Reactome: R-HSA-112383 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein"
5. Reactome: R-HSA-113503 "PP2A mediated localization of RB1 protein in chromatin"
6. Reactome: R-HSA-1363274 "Dephosphorylation of p107 (RBL1) by PP2A"
7. Reactome: R-HSA-1363276 "Dephosphorylation of p130 (RBL2) by PP2A"
8. Reactome: R-HSA-167072 "Hypophosphorylation of RNA Pol II CTD by FCP1P protein"
9. Reactome: R-HSA-170153 "Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases"
10. Reactome: R-HSA-170158 "Dephosphorylation of nuclear Cyclin A:phospho-Cdc2 complexes"
11. Reactome: R-HSA-170161 "Dephosphorylation of cytoplasmic Cyclin B1/B2:phospho-Cdc2 (Thr 14, Tyr 15) complexes by CDC25B"
12. Reactome: R-HSA-174110 "Cdc25A mediated dephosphorylation of Cyclin A:phospho-Cdk2"
13. Reactome: R-HSA-174124 "Dephosphorylation of phospho-Cdh1"
14. Reactome: R-HSA-178178 "PP1 dephosphorylates TGFBR1"
15. Reactome: R-HSA-2529015 "Dephosphorylation of CK2-modified condensin I"
16. Reactome: R-HSA-69199 "Dephosphorylation of Cyclin E:Cdk2 complexes by Cdc25A"
Legend
is an element of the parent element
is a part of the parent element
is related to the parent element
derives from the parent element
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Condensed Tree View
Gene ontology
biological_process is a
cellular process is a
cellular metabolic process is a
cellular macromolecule metabolic process is a
cellular protein metabolic process is a
cellular protein modification process is a
protein dephosphorylation is a
phosphoprotein phosphatase activity part of
Tree view
Gene ontology
biological_process is a
behavior is a
biological adhesion is a
biological phase is a
biological regulation is a
biomineralization is a
carbohydrate utilization is a
carbon utilization is a
cellular process is a
actin filament-based process is a
cell activation is a
cell adhesion molecule production is a
cell aggregation is a
cell communication is a
cell cycle is a
cell death is a
cell division is a
cell growth is a
cell killing is a
cell population proliferation is a
cell recognition is a
cell wall organization or biogenesis is a
cell-cell fusion is a
cellular component organization or biogenesis is a
cellular detoxification is a
cellular developmental process is a
cellular localization is a
cellular metabolic process is a
bioluminescence is a
cellular alcohol metabolic process is a
cellular aldehyde metabolic process is a
cellular alkane metabolic process is a
cellular alkene metabolic process is a
cellular alkyne metabolic process is a
cellular aromatic compound metabolic process is a
cellular biosynthetic process is a
cellular carbohydrate metabolic process is a
cellular catabolic process is a
cellular ketone body metabolic process is a
cellular ketone metabolic process is a
cellular lipid metabolic process is a
cellular macromolecule metabolic process is a
cellular protein metabolic process is a
CAAX-box protein maturation is a
cellular protein modification process is a
co-translational protein modification is a
enzyme active site formation is a
ISG15-protein conjugation is a
metal incorporation into metallo-molybdopterin complex is a
metal incorporation into metallo-oxygen cluster is a
N-terminal protein amino acid modification is a
nucleic acid-protein covalent cross-linking is a
peptide cross-linking is a
peptidyl-amino acid modification is a
post-translational protein modification is a
protein acylation is a
protein ADP-ribosylation is a
protein alkylation is a
protein amidation is a
protein biotinylation is a
protein carbamoylation is a
protein carboxylation is a
protein de-ADP-ribosylation is a
protein deacylation is a
protein dealkylation is a
protein deamination is a
protein deglutathionylation is a
protein deglycation is a
protein deglycosylation is a
protein dehydration is a
protein delipidation is a
protein denucleotidylation is a
protein dephosphorylation is a
peptidyl-histidine dephosphorylation is a
peptidyl-N-phospho-arginine dephosphorylation is a
peptidyl-serine dephosphorylation is a
peptidyl-threonine dephosphorylation is a
peptidyl-tyrosine dephosphorylation is a
phosphoprotein phosphatase activity part of
protein desulfurization is a
protein esterification is a
protein flavinylation is a
protein glucuronidation is a
protein glutathionylation is a
protein halogenation is a
protein hydroxylation is a
protein initiator methionine removal is a
protein modification by small protein conjugation or removal is a
protein nitrosylation is a
protein nucleotidylation is a
protein oxidation is a
protein phosphopantetheinylation is a
protein phosphorylation is a
protein polyamination is a
protein prenylation is a
protein sialylation is a
protein sulfation is a
protein sulfhydration is a
protein tyrosinylation is a
protein-chromophore linkage is a
protein-cofactor linkage is a
protein-tetrapyrrole linkage is a
ferredoxin metabolic process is a
mitochondrial protein processing is a
Notch receptor processing is a
prosthetic group metabolic process part of
protein repair is a
rhodopsin metabolic process is a
signal peptide processing is a
vacuolar protein processing is a
glycoprotein metabolic process is a
hemoglobin metabolic process is a
macromolecule methylation is a
poly-gamma-glutamate metabolic process is a
receptor metabolic process is a
cellular metabolic compound salvage is a
cellular modified amino acid metabolic process is a
cellular nitrogen compound metabolic process is a
cellular organohalogen metabolic process is a
chemosynthesis is a
cofactor metabolic process is a
drug metabolic process is a
generation of precursor metabolites and energy is a
heterocycle metabolic process is a
hydroperoxide metabolic process is a
metabolite repair is a
mucilage metabolic process is a
one-carbon metabolic process is a
organic acid metabolic process is a
organometal metabolic process is a
phosphorus metabolic process is a
2-aminoethylphosphonate metabolic process is a
organophosphate metabolic process is a
phosphate-containing compound metabolic process is a
dephosphorylation is a
DNA dephosphorylation is a
phosphatase activity part of
10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity is a
2-carboxy-D-arabinitol-1-phosphatase activity is a
2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity is a
2-phosphosulfolactate phosphatase activity is a
3',5'-nucleotide bisphosphate phosphatase activity is a
3-deoxy-manno-octulosonate-8-phosphatase activity is a
3-phosphoglycerate phosphatase activity is a
3-phytase activity is a
4-phytase activity is a
5'-deoxynucleotidase activity is a
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity is a
5-phytase activity is a
6-phosophogluco-3-phosphogluco-starch phosphatase activity is a
acid phosphatase activity is a
acireductone synthase activity is a
ADP-phosphoglycerate phosphatase activity is a
alkaline phosphatase activity is a
alkylacetylglycerophosphatase activity is a
alpha-ribazole phosphatase activity is a
aryldialkylphosphatase activity is a
bisphosphoglycerate phosphatase activity is a
caldesmon-phosphatase activity is a
carbohydrate phosphatase activity is a
D,D-heptose 1,7-bisphosphate phosphatase activity is a
deoxynucleotide 3'-phosphatase activity is a
dihydrosphingosine-1-phosphate phosphatase activity is a
dolichyl-phosphatase activity is a
ecdysone-phosphate phosphatase activity is a
ecdysteroid-phosphate phosphatase activity is a
FMN hydrolase activity is a
FMN phosphatase activity is a
fructose-1-phosphatase activity is a
glucosylglycerol 3-phosphatase activity is a
glycerol-1-phosphatase activity is a
glycerol-2-phosphatase activity is a
glycerol-3-phosphatase activity is a
guanidinodeoxy-scyllo-inositol-4-phosphatase activity is a
histidinol-phosphatase activity is a
inositol phosphate phosphatase activity is a
inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity is a
inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity is a
inositol bisphosphate phosphatase activity is a
inositol-1,4-bisphosphate 1-phosphatase activity is a
inositol-3,4-bisphosphate 4-phosphatase activity is a
inositol-4,5-bisphosphate 5-phosphatase activity is a
inositol monophosphate phosphatase activity is a
inositol pentakisphosphate phosphatase activity is a
inositol tetrakisphosphate phosphatase activity is a
inositol trisphosphate phosphatase activity is a
inositol-hexakisphosphate phosphatase activity is a
L-threonine O-3-phosphate phosphatase activity is a
lipid phosphatase activity is a
lysophosphatidic acid phosphatase activity is a
mannitol-1-phosphatase activity is a
mannosyl-3-phosphoglycerate phosphatase activity is a
methylphosphothioglycerate phosphatase activity is a
N-acylneuraminate-9-phosphatase activity is a
NADP phosphatase activity is a
NADPH phosphatase activity is a
NMN phosphatase activity is a
nucleotidase activity is a
nucleotide phosphatase activity, acting on free nucleotides is a
phosphatidate phosphatase activity is a
phosphatidylglycerophosphatase activity is a
phosphatidylinositol phosphate phosphatase activity is a
phosphatidylinositol-5-phosphate 5-phosphatase activity is a
phosphocholine phosphatase activity is a
phosphoenolpyruvate phosphatase activity is a
phosphoethanolamine phosphatase activity is a
phosphoglycerate phosphatase activity is a
phosphoglycolate phosphatase activity is a
phosphoserine phosphatase activity is a
pseudouridine 5'-phosphatase activity is a
pyridoxal phosphatase activity is a
ribitol-5-phosphatase activity is a
sedoheptulose-bisphosphatase activity is a
sorbitol-6-phosphatase activity is a
streptomycin-6-phosphatase activity is a
thymidylate 5'-phosphatase activity is a
phosphoanandamide dephosphorylation is a
polynucleotide 3' dephosphorylation is a
polynucleotide 5' dephosphorylation is a
phosphorylation is a
phosphorus utilization
photosynthesis is a
prenylation is a
reactive oxygen species metabolic process is a
selenium compound metabolic process is a
sulfur compound metabolic process is a
toxin metabolic process is a
xenobiotic metabolic process is a
cellular pigmentation is a
cellular process involved in reproduction in multicellular organism is a
cellular response to stimulus is a
chromosome segregation is a
cytolysis is a
DNA clamp unloading is a
ensheathment of neurons is a
establishment or maintenance of cell polarity is a
establishment or maintenance of cell type involved in phenotypic switching is a
export from cell is a
intercellular transport is a
intermediate filament-based process is a
light absorption is a
localization of cell is a
membrane docking is a
microtubule organizing center localization is a
microtubule-based process is a
movement of cell or subcellular component is a
multi-organism cellular process is a
phenotypic switching is a
plasmid maintenance is a
process utilizing autophagic mechanism is a
protein folding is a
protein unfolding is a
RNA folding is a
signaling receptor ligand precursor processing is a
stomatal movement is a
syncytium formation is a
transmembrane transport is a
transposition is a
vacuolar transport is a
vesicle-mediated transport is a
detoxification is a
developmental process is a
growth is a
immune system process is a
interspecies interaction between organisms is a
intraspecies interaction between organisms is a
localization is a
locomotion is a
metabolic process is a
multi-organism process is a
multicellular organismal process is a
pigmentation is a
reproduction is a
response to stimulus is a
rhythmic process is a
signaling is a
cellular_component is a
molecular_function is a