Ontology explorer

Gene ontology

Change ontology: Version 2014-12-22

Term or Synonym: use AND (NOT) or OR

Definition: use AND (NOT) or OR

Id:

restrict to BRENDA links:

Localization

Enzyme

Details for immunological synapse

immunological synapse

Gene ontology ID

GO:0001772

Definition

An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction

Synonyms

1. c-SMAC
2. supramolecular activation cluster

References

1. GOC: mgi curators
2. PMID 11244041
3. PMID 11376300
4. Wikipedia: Immunological synapse

Legend

is an element of the parent element

is a part of the parent element

is related to the parent element

derives from the parent element

at least 1 tissue/ enzyme/ localization link in this branch

tissue/ enzyme/ localization link to BRENDA

Condensed Tree View

Gene ontology

cellular_component is a

cellular anatomical entity is a

cell periphery is a

651 BRENDA localization in branch, click for list of all

plasma membrane part of

611 BRENDA localization in branch, click for list of all

immunological synapse part of

62 BRENDA localization in branch, click for list of all

plasma membrane region part of

Tree view

Gene ontology

biological_process is a

cellular_component is a

cell

cellular anatomical entity is a

A band

727 BRENDA localization in branch, click for list of all

acroblast

acrosomal matrix is a

724 BRENDA localization in branch, click for list of all

actin body is a

actin cap

723 BRENDA localization in branch, click for list of all

actin filament branch point is a

actin filament bundle is a

actin fusion focus is a

actin wave is a

actomyosin is a

717 BRENDA localization in branch, click for list of all

actomyosin contractile ring, distal actin filament layer is a

actomyosin contractile ring, intermediate layer is a

actomyosin contractile ring, proximal layer is a

alae of collagen and cuticulin-based cuticle extracellular matrix is a

annular furrow extracellular matrix is a

annuli extracellular matrix is a

apical complex is a

716 BRENDA localization in branch, click for list of all

apical cytoplasm is a

apical lamina of hyaline layer is a

apical part of cell is a

711 BRENDA localization in branch, click for list of all

ascus epiplasm is a

assemblon

axon collateral is a

709 BRENDA localization in branch, click for list of all

axon hillock is a

708 BRENDA localization in branch, click for list of all

axon initial segment is a

707 BRENDA localization in branch, click for list of all

axonemal basal plate is a

axonemal central apparatus is a

axonemal outer doublet is a

702 BRENDA localization in branch, click for list of all

axoneme

701 BRENDA localization in branch, click for list of all

bacterial biofilm matrix surface is a

bacterial-type flagellum basal body is a

bacterial-type flagellum filament is a

bacterial-type flagellum hook is a

bacterial-type flagellum hook-filament junction is a

basal labyrinth is a

basal layer of collagen and cuticulin-based cuticle extracellular matrix is a

basal part of cell is a

basolateral cytoplasm is a

bilobe structure is a

blood microparticle is a

Casparian strip is a

cell body

696 BRENDA localization in branch, click for list of all

cell division site is a

693 BRENDA localization in branch, click for list of all

cell junction is a

688 BRENDA localization in branch, click for list of all

cell leading edge is a

cell periphery is a

cell cortex part of

38 BRENDA localization in branch, click for list of all

external encapsulating structure part of

25 BRENDA localization in branch, click for list of all

plasma membrane part of

cell envelope

133 BRENDA localization in branch, click for list of all

cell trailing edge membrane part of

cellular bud membrane part of

cornified envelope is a

132 BRENDA localization in branch, click for list of all

cytoplasmic side of plasma membrane part of

cytoproct

cytostome

endomembrane system

130 BRENDA localization in branch, click for list of all

external side of plasma membrane part of

extrinsic component of plasma membrane part of

growth cone membrane part of

immunological synapse part of

intrinsic component of plasma membrane part of

lateral plasma membrane part of

53 BRENDA localization in branch, click for list of all

mesosome

52 BRENDA localization in branch, click for list of all

orthogonal array part of

51 BRENDA localization in branch, click for list of all

phagocytic cup part of

50 BRENDA localization in branch, click for list of all

plasma membrane protein complex part of

49 BRENDA localization in branch, click for list of all

plasma membrane region part of

apicolateral plasma membrane is a

basolateral plasma membrane is a

40 BRENDA localization in branch, click for list of all

caveola neck is a

cell projection membrane is a

periciliary membrane compartment is a

photoreceptor inner segment membrane is a

plasma membrane bounded cell projection

plasma membrane of cell tip is a

plasma membrane raft is a

plasma membrane-derived thylakoid membrane is a

sperm head plasma membrane is a

plasma membrane respirasome part of

plasma membrane-derived thylakoid lumen part of

porosome

3 BRENDA localization in branch, click for list of all

sarcolemma is a

2 BRENDA localization in branch, click for list of all

sperm plasma membrane is a

tetraspanin-enriched microdomain part of

unencapsulated part of cell

cell plate is a

476 BRENDA localization in branch, click for list of all

cell pole

475 BRENDA localization in branch, click for list of all

cell projection is a

cell septum is a

468 BRENDA localization in branch, click for list of all

cell surface is a

467 BRENDA localization in branch, click for list of all

cell tip

cell trailing edge is a

cellular bud is a

central element is a

465 BRENDA localization in branch, click for list of all

central plaque of spindle pole body is a

centriolar satellite is a

centrosomal corona is a

chiasma

464 BRENDA localization in branch, click for list of all

chromatin

463 BRENDA localization in branch, click for list of all

chromosomal region is a

446 BRENDA localization in branch, click for list of all

cnida

compact myelin is a

440 BRENDA localization in branch, click for list of all

concave side of sperm head is a

cone matrix sheath is a

contractile ring is a

439 BRENDA localization in branch, click for list of all

cortical layer of collagen and cuticulin-based cuticle extracellular matrix is a

costamere

cytoophidium is a

438 BRENDA localization in branch, click for list of all

cytoplasm

437 BRENDA localization in branch, click for list of all

deep fiber is a

dense fibrillar component is a

250 BRENDA localization in branch, click for list of all

dense nuclear body is a

dinoflagellate antapex is a

dinoflagellate apex is a

dinoflagellate epicone is a

dinoflagellate hypocone is a

DNA replication termination region is a

eisosome

249 BRENDA localization in branch, click for list of all

endonuclear canal is a

248 BRENDA localization in branch, click for list of all

endospore core is a

ensheathing process is a

envelope

247 BRENDA localization in branch, click for list of all

epicuticle of collagen and cuticulin-based cuticle extracellular matrix is a

extracellular matrix is a

246 BRENDA localization in branch, click for list of all

extracellular region is a

230 BRENDA localization in branch, click for list of all

extrachromosomal circular DNA is a

212 BRENDA localization in branch, click for list of all

extrachromosomal DNA is a

211 BRENDA localization in branch, click for list of all

extrinsic component of membrane is a

fibrillar center is a

Flemming body is a

gas vesicle shell is a

germ tube

209 BRENDA localization in branch, click for list of all

granular component is a

208 BRENDA localization in branch, click for list of all

half bridge of spindle pole body is a

host cellular component is a

incipient cellular bud site is a

inclusion body is a

193 BRENDA localization in branch, click for list of all

inner membrane pellicle complex is a

inner plaque of spindle pole body is a

intermediate layer of spindle pole body is a

intracellular immature spore is a

intrinsic component of membrane is a

investment cone is a

lateral element is a

lateral loop is a

lateral part of cell is a

leaflet of membrane bilayer is a

manchette

183 BRENDA localization in branch, click for list of all

median body is a

membrane

182 BRENDA localization in branch, click for list of all

membrane-enclosed lumen is a

metaphase plate is a

119 BRENDA localization in branch, click for list of all

microtubule bundle is a

microtubule end is a

118 BRENDA localization in branch, click for list of all

microtubule organizing center is a

116 BRENDA localization in branch, click for list of all

midbody

107 BRENDA localization in branch, click for list of all

myelin sheath is a

106 BRENDA localization in branch, click for list of all

neck portion of tanycyte is a

nucleoid

105 BRENDA localization in branch, click for list of all

nucleus lagging edge is a

nucleus leading edge is a

oral apparatus is a

103 BRENDA localization in branch, click for list of all

organelle

102 BRENDA localization in branch, click for list of all

pellicle

10 BRENDA localization in branch, click for list of all

periplasmic space is a

9 BRENDA localization in branch, click for list of all

photoreceptor inner segment is a

8 BRENDA localization in branch, click for list of all

polar tube is a

7 BRENDA localization in branch, click for list of all

site of polarized growth is a

6 BRENDA localization in branch, click for list of all

somatodendritic compartment is a

sperm head is a

5 BRENDA localization in branch, click for list of all

sperm head-tail coupling apparatus is a

sporoplasm is a

subapical part of cell is a

supramolecular complex is a

4 BRENDA localization in branch, click for list of all

symplast

tail portion of tanycyte is a

thylakoid

Yb body

intracellular is a

81 BRENDA localization in branch, click for list of all

other organism part is a

protein-containing complex is a

55 BRENDA localization in branch, click for list of all

virion

molecular_function is a