BRENDA - Enzyme Database show

Carnosine-synthetase inhibition by beta-alanine analogues

Seely, J.E.; Marshall, F.D.; Life Sci. 30, 1763-1768 (1982)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
6.3.2.11
2-Aminoethylphosphonic acid
weak
Gallus gallus
6.3.2.11
2-Aminoethylphosphonic acid
weak
Rattus norvegicus
6.3.2.11
3-Aminopropane sulfonic acid
competitive with respect to beta-Ala
Gallus gallus
6.3.2.11
3-Aminopropane sulfonic acid
competitive with respect to beta-Ala
Rattus norvegicus
6.3.2.11
3-Aminopropanephosphonic acid
-
Rattus norvegicus
6.3.2.11
5-Aminopentanoate
no inhibition
Gallus gallus
6.3.2.11
5-Aminopentanoate
-
Rattus norvegicus
6.3.2.11
Aminooxyacetate
-
Rattus norvegicus
6.3.2.11
Nipecotic acid
-
Rattus norvegicus
6.3.2.11
O-Phosphoethanolamine
weak
Gallus gallus
6.3.2.11
O-Phosphoethanolamine
weak
Rattus norvegicus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
6.3.2.11
Gallus gallus
-
-
-
6.3.2.11
Rattus norvegicus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
6.3.2.11
brain
-
Gallus gallus
-
6.3.2.11
brain
-
Rattus norvegicus
-
6.3.2.11
heart
-
Gallus gallus
-
6.3.2.11
heart
-
Rattus norvegicus
-
6.3.2.11
muscle
skeletal
Gallus gallus
-
6.3.2.11
muscle
skeletal
Rattus norvegicus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.2.11
ATP + L-His + beta-Ala
-
989
Gallus gallus
ADP + phosphate + carnosine
-
989
Gallus gallus
-
6.3.2.11
ATP + L-His + beta-Ala
-
989
Rattus norvegicus
ADP + phosphate + carnosine
-
989
Rattus norvegicus
-
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
6.3.2.11
2-Aminoethylphosphonic acid
weak
Gallus gallus
6.3.2.11
2-Aminoethylphosphonic acid
weak
Rattus norvegicus
6.3.2.11
3-Aminopropane sulfonic acid
competitive with respect to beta-Ala
Gallus gallus
6.3.2.11
3-Aminopropane sulfonic acid
competitive with respect to beta-Ala
Rattus norvegicus
6.3.2.11
3-Aminopropanephosphonic acid
-
Rattus norvegicus
6.3.2.11
5-Aminopentanoate
no inhibition
Gallus gallus
6.3.2.11
5-Aminopentanoate
-
Rattus norvegicus
6.3.2.11
Aminooxyacetate
-
Rattus norvegicus
6.3.2.11
Nipecotic acid
-
Rattus norvegicus
6.3.2.11
O-Phosphoethanolamine
weak
Gallus gallus
6.3.2.11
O-Phosphoethanolamine
weak
Rattus norvegicus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
6.3.2.11
brain
-
Gallus gallus
-
6.3.2.11
brain
-
Rattus norvegicus
-
6.3.2.11
heart
-
Gallus gallus
-
6.3.2.11
heart
-
Rattus norvegicus
-
6.3.2.11
muscle
skeletal
Gallus gallus
-
6.3.2.11
muscle
skeletal
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
6.3.2.11
ATP + L-His + beta-Ala
-
989
Gallus gallus
ADP + phosphate + carnosine
-
989
Gallus gallus
-
6.3.2.11
ATP + L-His + beta-Ala
-
989
Rattus norvegicus
ADP + phosphate + carnosine
-
989
Rattus norvegicus
-