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Literature summary extracted from

  • Sudbeck, H.D.; Jeffrey, J.J.; Welgus, H.G.; Mecham, R.P.; McCourt, D.; Parks, W.C.
    Purification and characterization of bovine interstitial collagenase and tissue inhibitor metalloproteinases (1992), Arch. Biochem. Biophys., 293, 370-376.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.24.7 0.0002
-
 bovine type I collagen
-
 Bos taurus
3.4.24.7 0.0005
-
 human type I collagen
-
 Bos taurus
3.4.24.7 0.0008
-
 human type I collagen
-
 Homo sapiens
3.4.24.7 0.0009
-
 human type I collagen
-
 Rattus norvegicus
3.4.24.7 0.001
-
 human type II collagen
-
 Bos taurus
3.4.24.7 0.0011
-
 human type I collagen
-
 Rattus norvegicus
3.4.24.7 0.0013
-
 human type III collagen
-
 Homo sapiens
3.4.24.7 0.0017
-
 human type III collagen
-
 Rattus norvegicus
3.4.24.7 0.0021
-
 human type II collagen
-
 Homo sapiens
3.4.24.7 0.0024
-
 human type III collagen
-
 Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
3.4.24.7 Bos taurus
-
-
-
3.4.24.7 Homo sapiens
-
-
-
3.4.24.7 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.24.7
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.24.7 skin
-
 Rattus norvegicus
-
3.4.24.7 skin
-
 Bos taurus
-
3.4.24.7 skin from the lateral thoracic area of a 230 day fetal calf Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.24.7 bovine type I collagen + H2O
-
 Bos taurus ?
-
 ?
3.4.24.7 human type I collagen + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.7 human type I collagen + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.24.7 human type I collagen + H2O
-
 Bos taurus ?
-
 ?
3.4.24.7 human type II collagen + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.7 human type II collagen + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.24.7 human type II collagen + H2O
-
 Bos taurus ?
-
 ?
3.4.24.7 human type III collagen + H2O
-
 Homo sapiens ?
-
 ?
3.4.24.7 human type III collagen + H2O
-
 Rattus norvegicus ?
-
 ?
3.4.24.7 human type III collagen + H2O
-
 Bos taurus ?
-
 ?

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.24.7 0.000267
-
 human type II collagen
-
 Homo sapiens
3.4.24.7 0.000383
-
 human type II collagen
-
 Rattus norvegicus
3.4.24.7 0.00147
-
 bovine type I collagen
-
 Bos taurus
3.4.24.7 0.0035
-
 human type I collagen
-
 Bos taurus
3.4.24.7 0.00375
-
 human type I collagen
-
 Rattus norvegicus
3.4.24.7 0.00392
-
 human type II collagen
-
 Rattus norvegicus
3.4.24.7 0.0056
-
 human type III collagen
-
 Homo sapiens
3.4.24.7 0.0148
-
 human type I collagen
-
 Homo sapiens
3.4.24.7 0.0958
-
 human type III collagen
-
 Bos taurus
3.4.24.7 0.153
-
 human type III collagen
-
 Homo sapiens