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Literature summary extracted from
- The cysteine proteinases (1976), Tetrahedron, 32, 291-302.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.22.2 | Chloroacetate | - |
Carica papaya |  |
| 3.4.22.2 | iodoacetic acid | - |
Carica papaya | |
| 3.4.22.2 | L-Ala-L-Phe-aminoacetonitrile | - |
Carica papaya | |
| 3.4.22.2 | N-benzyloxycarbonyl-L-Phe-L-Ala chloromethyl ketone | - |
Carica papaya | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.22.2 | Carica papaya | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.22.2 | side-chain modification | propapain is activated by intramolecular thiol-disulfide exchange which is catalyzed by cysteine | Carica papaya |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.22.2 | latex | - |
Carica papaya | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.22.2 | Glucagon + H2O | - |
Carica papaya | ? | - |
? | |
| 3.4.22.2 | Hemoglobin + H2O | alpha-chain and beta-chain | Carica papaya | ? | - |
? | |
| 3.4.22.2 | oxidized beta-chain of insulin + H2O | - |
Carica papaya | ? | - |
? | |
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Release 2023.1 (January 2023)
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