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Literature summary extracted from

  • Wang, X.; Lin, X.; Loy, J.A.; Tang, J.; Zhang, X.C.
    Crystal structure of the catalytic structure of the catalytic domain of human plasmin complexed with streptokinase (1998), Science, 281, 1662-1665.
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.21.7 crystal structure of plasmin complexed with streptokinase Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.21.7 Fibrin + H2O Homo sapiens the activation of plasminogen in blood plasma is the central event that results in the dissolution of the fibrin clot by proteolysis ?
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Organism

EC Number Organism UniProt Comment Textmining
3.4.21.7 Homo sapiens
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.7 Fibrin + H2O the activation of plasminogen in blood plasma is the central event that results in the dissolution of the fibrin clot by proteolysis Homo sapiens ?
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 ?
3.4.21.7 additional information complexes of streptokinase with human plasminogen can hydrolytically activate other plasminogen molecules to plasmin, which then dissolve blood clots Homo sapiens ?
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 ?