Any feedback?
Literature summary extracted from
- Plasminogen and plasmin (1976), Methods Enzymol., 45, 257-273.
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.21.7 | 25700 | - |
x * 48800, A-chain, + x * 25700, B-chain, equilibrium sedimentation after cleavage of a single disulfide bond in Lys-plasminogen | Homo sapiens |
| 3.4.21.7 | 48800 | - |
x * 48800, A-chain, + x * 25700, B-chain, equilibrium sedimentation after cleavage of a single disulfide bond in Lys-plasminogen | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.7 | Homo sapiens | - |
- |
- |
| 3.4.21.7 | Oryctolagus cuniculus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.21.7 | proteolytic modification | activation of plasminogen by cleavage of a sensitive Arg-Val peptide bond in the COOH-terminal portion of Glu-plasminogen to give the two-chain plasmin molecule, followed by the cleavage of a Lys-Lys peptide bond in the NH2-terminal portion of the molecule. The latter event results in the release of a peptide, or peptides | Homo sapiens |
| 3.4.21.7 | proteolytic modification | zymogen: plasminogen | Homo sapiens |
| 3.4.21.7 | proteolytic modification | zymogen: plasminogen | Oryctolagus cuniculus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.21.7 | plasma | - |
Homo sapiens | - |
| 3.4.21.7 | serum | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.7 | Fibrin + H2O | - |
Homo sapiens | ? | - |
? |  |
| 3.4.21.7 | Fibrin + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
| 3.4.21.7 | plasminogen + H2O | - |
Homo sapiens | ? | - |
? | |
| 3.4.21.7 | plasminogen + H2O | - |
Oryctolagus cuniculus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.21.7 | monomer | - |
Oryctolagus cuniculus |
| 3.4.21.7 | monomer | x * 48800, A-chain, + x * 25700, B-chain, equilibrium sedimentation after cleavage of a single disulfide bond in Lys-plasminogen | Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
