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Literature summary extracted from

  • Folk, J.E.; Schirmer, E.W.
    Chymotrypsin C. I. Isolation of the zymogen and the active enzyme: preliminary structure and specificity studies (1965), J. Biol. Chem., 240, 181-192.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.21.2 DFP
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.21.2 10
-
 benzoyl-L-Met ethyl ester
-
 Sus scrofa
3.4.21.2 15
-
 benzyloxycarbonyl-L-Leu-Gly-amide
-
 Sus scrofa
3.4.21.2 17
-
 benzoyl-L-Met ethyl ester
-
 Sus scrofa
3.4.21.2 28
-
 benzoyl-L-Leu ethyl ester
-
 Sus scrofa

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.21.2 31800
-
 x * 31800, calculation from amino acid sequence Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.2 Sus scrofa
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.4.21.2 proteolytic modification zymogen: chymotrypsinogen C Sus scrofa

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.21.2
-
 Sus scrofa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.2 pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.21.2 A chain of oxidized insulin + H2O
-
 Sus scrofa ?
-
 ?
3.4.21.2 acetyl-L-Trp ethyl ester + H2O
-
 Sus scrofa acetyl-L-Trp + ethanol
-
 ?
3.4.21.2 B chain of oxidized insulin + H2O
-
 Sus scrofa ?
-
 ?
3.4.21.2 benzoyl-L-Met ethyl ester + H2O
-
 Sus scrofa benzoyl-L-Met + ethanol
-
 ?
3.4.21.2 benzoyl-L-Tyr ethyl ester + H2O
-
 Sus scrofa benzoyl-L-Tyr + ethanol
-
 ?
3.4.21.2 benzoyl-Leu-ethyl ester + H2O
-
 Sus scrofa benzoyl-Leu + ethanol
-
 ?
3.4.21.2 benzoyl-Phe ethyl ester + H2O
-
 Sus scrofa benzoyl-Phe + ethanol
-
 ?
3.4.21.2 benzyloxycarbonyl-L-Leu-Gly-amide + H2O
-
 Sus scrofa benzyloxycarbonyl-L-Leu-Gly + NH3
-
 ?
3.4.21.2 carboxymethylated reduced ribonuclease + H2O
-
 Sus scrofa ?
-
 ?
3.4.21.2 Glucagon + H2O
-
 Sus scrofa ?
-
 ?
3.4.21.2 oxidized oxytocin + H2O
-
 Sus scrofa ?
-
 ?
3.4.21.2 p-nitrophenyl acetate + H2O
-
 Sus scrofa p-nitrophenol + acetate
-
 ?
3.4.21.2 Ser-His-Leu-Val-Glu + H2O
-
 Sus scrofa ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.21.2 ? x * 31800, calculation from amino acid sequence Sus scrofa

Turnover Number [1/s]

EC Number Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.4.21.2 0.013
-
 benzyloxycarbonyl-L-Leu-Gly amide
-
 Sus scrofa
3.4.21.2 0.32
-
 acetyl-L-Trp ethyl ester
-
 Sus scrofa
3.4.21.2 1.55
-
 benzoyl-L-Phe ethyl ester
-
 Sus scrofa
3.4.21.2 1.7
-
 benzoyl-L-Met ethyl ester
-
 Sus scrofa
3.4.21.2 25.4
-
 benzoyl-L-Leu ethyl ester
-
 Sus scrofa
3.4.21.2 46
-
 benzoyl-L-Tyr ethyl ester
-
 Sus scrofa