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Literature summary extracted from
- Thyrotropin-releasing hormone-degrading enzyme in human serum is classified as type II of pyroglutamyl aminopeptidase: influence of thyroid status (1990), Proc. Soc. Exp. Biol. Med., 194, 346-351.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.19.3 | 1,10-phenanthroline | - |
Homo sapiens |  |
| 3.4.19.3 | DTT | - |
Homo sapiens | |
| 3.4.19.3 | EDTA | - |
Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.19.3 | 0.0449 | - |
pyroglutamyl-His-Pro-NH2 | - |
Homo sapiens | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.19.3 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.19.3 | serum | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.19.3 | thyroliberin + H2O | - |
Homo sapiens | pyroglutamate + His-Pro-NH2 | - |
? | |
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