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Literature summary extracted from

  • Sakai, T.; Kojima, K.
    Rapid chromatographic purification of dipeptidyl-aminopeptidase II from human kidney (1987), J. Chromatogr., 416, 131-137.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.14.2 bestatin
-
 Homo sapiens
3.4.14.2 diisopropyl fluorophosphate
-
 Homo sapiens
3.4.14.2 phenylmethylsulfonyl fluoride
-
 Homo sapiens
3.4.14.2 Tris
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.14.2 0.0457
-
 Ala-Pro-4-nitroanilide
-
 Homo sapiens
3.4.14.2 0.0457
-
 Lys-Pro-4-nitroanilide
-
 Homo sapiens
3.4.14.2 0.086
-
 Arg-Pro-4-nitroanilide
-
 Homo sapiens
3.4.14.2 0.282
-
 Gly-Pro-4-nitroanilide
-
 Homo sapiens
3.4.14.2 0.311
-
 Glu-Pro-4-nitroanilide
-
 Homo sapiens
3.4.14.2 0.93
-
 L-Lys-L-Ala-7-amido-4-methylcoumarin
-
 Homo sapiens
3.4.14.2 1.16
-
 Asp-Pro-4-nitroanilide
-
 Homo sapiens
3.4.14.2 1.22
-
 Ala-Ala-4-nitroanilide
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.14.2 55000
-
 2 * 55000, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.14.2 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.14.2
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.14.2 kidney
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.14.2 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.14.2 Ala-Ala-4-nitroanilide + H2O
-
 Homo sapiens Ala-Ala + 4-nitroaniline
-
 ?
3.4.14.2 Ala-Pro-4-nitroanilide + H2O
-
 Homo sapiens Ala-Pro + 4-nitroaniline
-
 ?
3.4.14.2 Arg-Pro-4-nitroanilide + H2O
-
 Homo sapiens Arg-Pro + 4-nitroaniline
-
 ?
3.4.14.2 Asp-Pro-4-nitroanilide + H2O
-
 Homo sapiens Asp-Pro + 4-nitroaniline
-
 ?
3.4.14.2 Glu-Pro-4-nitroanilide + H2O
-
 Homo sapiens Glu-Pro + 4-nitroaniline
-
 ?
3.4.14.2 Gly-Pro-4-nitroanilide + H2O
-
 Homo sapiens Gly-Pro + 4-nitroaniline
-
 ?
3.4.14.2 L-Lys-L-Ala-7-amido-4-methylcoumarin + H2O
-
 Homo sapiens L-Lys-L-Ala + 7-amino-4-methylcoumarin
-
 ?
3.4.14.2 Lys-Ala-4-methylcoumaryl-7-amide + H2O
-
 Homo sapiens Lys-Ala + 7-amino-4-methylcoumarin
-
 ?
3.4.14.2 Lys-Pro-4-nitroanilide + H2O
-
 Homo sapiens Lys-Pro + 4-nitroaniline
-
 ?

Subunits

EC Number Subunits Comment Organism
3.4.14.2 dimer 2 * 55000, SDS-PAGE Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.14.2 5.3
-
 hydrolysis of Lys-Ala-4-methylcoumarinamide Homo sapiens