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Literature summary extracted from
- Purification and enzymatic properties of an L-leucine aminopeptidase from swine liver (1981), Biochim. Biophys. Acta, 660, 262-270.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.1 | Citric acid | - |
Sus scrofa |  |
| 3.4.11.1 | Dodecylamino aliphatic alcohols | - |
Sus scrofa | |
| 3.4.11.1 | Isocaproic acid | - |
Sus scrofa | |
| 3.4.11.1 | p-chloromercuribenzoate | - |
Sus scrofa | |
| 3.4.11.1 | Zn2+ | - |
Sus scrofa | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.4.11.1 | cytoplasm | - |
Sus scrofa | 5737 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.1 | Mg2+ | activation | Sus scrofa | |
| 3.4.11.1 | Mn2+ | activation | Sus scrofa | |
| 3.4.11.1 | Zn2+ | 4-6 gatom per mol | Sus scrofa | |
| 3.4.11.1 | Zn2+ | 11.4 gatom per mol | Sus scrofa | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 268000 | 270000 | gel filtration | Sus scrofa |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.1 | Sus scrofa | - |
hog | - |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.11.1 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | additional information | - |
- |
Sus scrofa |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.1 | amino acid amides + H2O | slow hydrolysis: Tyr, Phe | Sus scrofa | amino acid + NH3 | - |
? | |
| 3.4.11.1 | amino acid amides + H2O | fast hydrolysis: L-Leu | Sus scrofa | amino acid + NH3 | - |
? | |
| 3.4.11.1 | L-amino acid-peptide + H2O | Leu-Gly-Gly | Sus scrofa | amino acid + peptide | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 10 | - |
- |
Sus scrofa |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 7 | - |
no activity below | Sus scrofa |
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Release 2023.1 (January 2023)
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