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Literature summary extracted from
- Purification and characterization of leucine aminopeptidase from human cerebral cortex (1988), Biochem. Soc. Trans., 16, 850-851.
No PubMed abstract available
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.1 | 1,10-phenanthroline | - |
Homo sapiens |  |
| 3.4.11.1 | amastatin | - |
Homo sapiens | |
| 3.4.11.1 | bestatin | - |
Homo sapiens | |
| 3.4.11.1 | p-Hydroxymercuriphenylsulfonate | - |
Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.11.1 | 1.25 | - |
leucine-7-amido-4-methylcoumarin | - |
Homo sapiens | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.11.1 | Mg2+ | activation | Homo sapiens | |
| 3.4.11.1 | Mn2+ | activation | Homo sapiens | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 268000 | 270000 | gel filtraton | Homo sapiens |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.1 | additional information | Homo sapiens | - |
? | - |
? | |
| 3.4.11.1 | Proteins + H2O | Homo sapiens | Leu5-enkephalin | ? | - |
? | |
| 3.4.11.1 | Proteins + H2O | Homo sapiens | e.g. luliberin | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.11.1 | Homo sapiens | - |
- |
- |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.11.1 | - |
Homo sapiens |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.11.1 | cerebral cortex | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.11.1 | Leu-7-amido-4-methylcoumarin + H2O | Leu replaced by Met | Homo sapiens | leucine + 7-amino-4-methylcoumarin | - |
? | |
| 3.4.11.1 | additional information | - |
Homo sapiens | ? | - |
? | |
| 3.4.11.1 | Proteins + H2O | Leu5-enkephalin | Homo sapiens | ? | - |
? | |
| 3.4.11.1 | Proteins + H2O | e.g. luliberin | Homo sapiens | ? | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.4.11.1 | 9.5 | - |
- |
Homo sapiens |
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Release 2023.1 (January 2023)
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