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Literature summary extracted from

  • Leder, I.G.
    A novel 3-O sulfatase from human urine acting on methyl-2-deoxy-2-sulfamid-alpha-D-glucopyranoside 3-sulfate (1980), Biochem. Biophys. Res. Commun., 94, 1183-1189.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.6.15 PO43- 50% reduction of activity at 0.1 mM Homo sapiens
3.1.6.15 SO42- 50% reduction of activity at 0.8 mM Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.6.15 N2-sulfo-D-glucosamine 3-sulfate units + H2O Homo sapiens of heparin ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.15 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.15 70fold Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.6.15 fibroblast
-
 Homo sapiens
-
3.1.6.15 urine
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.15 methyl-2-deoxy-2-sulfamino-alpha-D-glucopyranoside 3-sulfate + H2O
-
 Homo sapiens methyl-2-deoxy-2-sulfamino-alpha-D-glucopyranoside + sulfate
-
 ?
3.1.6.15 additional information not: 4- and 6-O-sulfate esters Homo sapiens ?
-
 ?
3.1.6.15 N2-sulfo-D-glucosamine 3-sulfate unit + H2O of heparin Homo sapiens D-glucosamine units + sulfate of heparin ?
3.1.6.15 N2-sulfo-D-glucosamine 3-sulfate units + H2O of heparin Homo sapiens ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.6.15 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.6.15 6.3
-
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.6.15 5 7.2 less than 60% of maximal activity above and below Homo sapiens