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Literature summary extracted from

  • Anfuso, C.D.; Sipione S.; Lupo, G.; Alberghina, M.
    Evolutionary comparison of enzyme activities of phosphatidylcholine metabolism in the nervous system of an invertebrate (Loligo pealei), lower vertebrate (Mustelus canis) and the rat (1995), Comp. Biochem. Physiol. B, 112, 493-501.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.4.2 L-alpha-glycerol 3-phosphate
-
 Doryteuthis pealeii
3.1.4.2 L-alpha-glycerol 3-phosphate
-
 Mustelus canis
3.1.4.2 L-alpha-glycerol 3-phosphate higher inhition than in Loligo pealei or Mustelus canis Rattus sp.
3.1.4.2 N-ethylmaleimide
-
 Doryteuthis pealeii
3.1.4.2 N-ethylmaleimide
-
 Mustelus canis
3.1.4.2 N-ethylmaleimide higher inhibition than in Loligo pealei or Mustelus canis Rattus sp.
3.1.4.2 Zn2+
-
 Doryteuthis pealeii
3.1.4.2 Zn2+
-
 Mustelus canis
3.1.4.2 Zn2+ higher inhibition than in Loligo pealei or Mustelus canis Rattus sp.

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.4.2 4.5
-
 sn-glycero 3-phosphocholine
-
 Doryteuthis pealeii
3.1.4.2 5.7
-
 sn-glycero 3-phosphocholine
-
 Rattus sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O Rattus sp. cellular phosphatidylcholine catabolic pathway ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O Doryteuthis pealeii cellular phosphatidylcholine catabolic pathway ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O Mustelus canis cellular phosphatidylcholine catabolic pathway ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylethanolamine + H2O Rattus sp. cellular phosphatidyethanolamine catabolic pathway ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylethanolamine + H2O Doryteuthis pealeii cellular phosphatidyethanolamine catabolic pathway ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.4.2 Doryteuthis pealeii
-
-
-
3.1.4.2 Mustelus canis
-
-
-
3.1.4.2 Rattus sp.
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.4.2 brain
-
 Rattus sp.
-
3.1.4.2 brain
-
 Mustelus canis
-
3.1.4.2 optic lobe
-
 Doryteuthis pealeii
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.4.2 0.001
-
-
 Doryteuthis pealeii
3.1.4.2 0.006
-
-
 Rattus sp.

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + choline
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O
-
 Doryteuthis pealeii sn-glycerol 3-phosphate + choline
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O
-
 Mustelus canis sn-glycerol 3-phosphate + choline
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Rattus sp. ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Doryteuthis pealeii ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylcholine + H2O cellular phosphatidylcholine catabolic pathway Mustelus canis ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylethanolamine + H2O
-
 Rattus sp. sn-glycerol 3-phosphate + ethanolamine
-
 ?
3.1.4.2 sn-glycero 3-phosphorylethanolamine + H2O
-
 Doryteuthis pealeii sn-glycerol 3-phosphate + ethanolamine
-
 ?
3.1.4.2 sn-glycero 3-phosphorylethanolamine + H2O cellular phosphatidyethanolamine catabolic pathway Rattus sp. ?
-
 ?
3.1.4.2 sn-glycero 3-phosphorylethanolamine + H2O cellular phosphatidyethanolamine catabolic pathway Doryteuthis pealeii ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.4.2 GroPChoPDE
-
 Rattus sp.
3.1.4.2 GroPChoPDE
-
 Doryteuthis pealeii
3.1.4.2 GroPChoPDE
-
 Mustelus canis