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Literature summary extracted from

  • Brunati, A.M.; Pinna, L.A.
    Isolation and partial characterization of distinct species of phosphotyrosyl protein phosphatases from rat spleen (1985), Biochem. Biophys. Res. Commun., 133, 929-936.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.48 EDTA activation Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.48 H3VO4 no effect on PTP-I but PTP-III inhibited Rattus norvegicus
3.1.3.48 molybdate no effect on PTP-I, PTP-III inhibited Rattus norvegicus
3.1.3.48 Zn2+
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.48 cytosol 20-30% membrane-bound, 70-80% cytosolic Rattus norvegicus 5829
-
3.1.3.48 plasma membrane 20-30% membrane-bound, 70-80% cytosolic Rattus norvegicus 5886
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.48 30000
-
 PTP-II, gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.48 Rattus norvegicus
-
 enzymes PTP-I, PTP-II, PTP-III
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.48
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.48 spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.48 phosphotyrosine serum albumin + H2O
-
 Rattus norvegicus ? + phosphate
-
 ?
3.1.3.48 poly(Glu,Tyr) + H2O
-
 Rattus norvegicus ? + phosphate
-
 ?