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Literature summary extracted from

  • Waheed, A.; Laidler, P.M.; Wo, Y.Y.P.; Van Etten, R.L.
    Purification and physicochemical characterization of a human placental acid phosphatase possessing phosphotyrosyl protein phosphatase activity (1988), Biochemistry, 27, 4265-4273.
    View publication on PubMed

General Stability

EC Number General Stability Organism
3.1.3.48 EDTA and dithiothreitol stabilize Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.48 DNA
-
 Homo sapiens
3.1.3.48 H3VO4
-
 Homo sapiens
3.1.3.48 L-Tartrate weak Homo sapiens
3.1.3.48 molybdate
-
 Homo sapiens
3.1.3.48 NaF weak Homo sapiens
3.1.3.48 tungstate
-
 Homo sapiens
3.1.3.48 Zn2+
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.48 0.169
-
 4-nitrophenyl phosphate pH 5 Homo sapiens
3.1.3.48 1.6
-
 phosphotyrosine
-
 Homo sapiens
3.1.3.48 2.1
-
 4-nitrophenyl phosphate pH 7 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.3.48 cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.3.48 16900
-
 x * 16900, SDS-PAGE Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.48 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.3.48 no modification
-
 Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.48
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.48 placenta
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.3.48 106
-
 substrate 4-nitrophenyl phosphate Homo sapiens

Storage Stability

EC Number Storage Stability Organism
3.1.3.48 4°C, 10 mM phosphate, 10 mM sodium acetate, pH 5.0, 0.5 mg/ml enzyme, 10% v/v glycerol, stable for 6 months Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.48 4-nitrophenyl phosphate + H2O
-
 Homo sapiens 4-nitrophenol + phosphate
-
 ?
3.1.3.48 angiotensin I + H2O
-
 Homo sapiens ? + phosphate
-
 ?
3.1.3.48 membrane protein 3 + H2O
-
 Homo sapiens ? + phosphate
-
 ?
3.1.3.48 additional information no hydrolysis of serine phosphate, threonine phosphate, nicotinamide adenine dinucleotide phosphate Homo sapiens ?
-
 ?
3.1.3.48 phosphotyrosine + H2O
-
 Homo sapiens tyrosine + phosphate
-
 ?
3.1.3.48 tyrosin kinase + H2O
-
 Homo sapiens ? + phosphate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.3.48 ? x * 16900, SDS-PAGE Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.48 5 7
-
 Homo sapiens

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.3.48 3 8
-
 Homo sapiens