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Literature summary extracted from

  • Gil, G.; Sitges, M.; Bove, J.; Hegardt, G.
    Phosphorylation-dephosphorylation of rat liver 3-hydroxy 3-methylglutaryl coenzyme A reductase associated with changes in activity (1980), FEBS Lett., 110, 195-199.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.47 fluoride
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O Rattus norvegicus
-
 ?
-
 ?

Organic Solvent Stability

EC Number Organic Solvent Comment Organism
3.1.3.47 Ethanol after treatment with this solvent a catalytic subunit of 32000-35000 Da is obtained, activity increased Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.47 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.47 liver Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.47 liver
-
 Rattus norvegicus
-

Storage Stability

EC Number Storage Stability Organism
3.1.3.47 -40°C, several months, no measurable loss of activity Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O
-
 Rattus norvegicus [hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate
-
 ?
3.1.3.47 [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O
-
 Rattus norvegicus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.47 8.5
-
 for the catalytic subunit of 32000-35000 Da retrieved after ethanol treatment Rattus norvegicus