EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.47 | diphosphate | - |
Rattus norvegicus | |
3.1.3.47 | fluoride | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.47 | cytosol | - |
Rattus norvegicus | 5829 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.3.47 | 120000 | - |
cytosolic isoenzyme II, gel chromatography | Rattus norvegicus |
3.1.3.47 | 190000 | - |
cytosolic isoenzyme I, gel chromatography | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.47 | [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O | Rattus norvegicus | - |
? | - |
? |
EC Number | Organic Solvent | Comment | Organism |
---|---|---|---|
3.1.3.47 | Acetone | after treatment with acetone a catalytic subunit of ~35000 Da is obtained, activity increased | Rattus norvegicus |
3.1.3.47 | Ethanol | after treatment with this solvent a catalytic subunit of 32000-35000 Da is obtained, activity increased | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.47 | Rattus norvegicus | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.1.3.47 | liver | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.47 | intestine | - |
Rattus norvegicus | - |
3.1.3.47 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.47 | HMG-CoA reductase kinase phosphate + H2O | - |
Rattus norvegicus | HMG-CoA reductase kinase + phosphate | - |
? | |
3.1.3.47 | phosphorylase a phosphate + H2O | - |
Rattus norvegicus | phosphorylase a + phosphate | - |
? | |
3.1.3.47 | [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O | - |
Rattus norvegicus | [hydroxymethylglutaryl-CoA reductase (NADPH)] + phosphate | - |
? | |
3.1.3.47 | [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate + H2O | - |
Rattus norvegicus | ? | - |
? |