EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.43 | EGTA | inhibits binding of the phosphatase to transacetylase | Bos taurus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.3.43 | 0.029 | - |
[Pyruvate dehydrogenase (lipoamide)]-phosphate | presence of Ca2+ and transacetylase | Bos taurus | |
3.1.3.43 | 0.058 | - |
[Pyruvate dehydrogenase (lipoamide)]-phosphate | presence of EGTA and transacetylase | Bos taurus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.43 | mitochondrion | - |
Bos taurus | 5739 | - |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.3.43 | Ca2+ | required to bind the phosphatase to the transacetylase | Bos taurus | |
3.1.3.43 | Mg2+ | required | Bos taurus |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
3.1.3.43 | 100000 | - |
- |
Bos taurus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.43 | [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | Bos taurus | - |
? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.43 | Bos taurus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.3.43 | heart | - |
Bos taurus | - |
3.1.3.43 | kidney | - |
Bos taurus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.43 | [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | presence of EGTA or Ca2+ and transacetylase | Bos taurus | [pyruvate dehydrogenase (lipoamide)] + phosphate | - |
ir | |
3.1.3.43 | [pyruvate dehydrogenase (lipoamide)]-phosphate + H2O | - |
Bos taurus | ? | - |
? |