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Literature summary extracted from

  • Barker, H.A.; D'Ari, L.; Kahn, J.
    Enzymatic reactions in the degradation of 5-aminovalerate by Clostridium aminovalericum (1987), J. Biol. Chem., 262, 8994-9003.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.6.1.48 2-mercaptoethanol
-
 Anaerocolumna aminovalerica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.6.1.48 4
-
 delta-aminovaleric acid pH 8.2, 37°C Anaerocolumna aminovalerica
2.6.1.48 4.7
-
 2-oxoglutarate pH 8.2, 37°C Anaerocolumna aminovalerica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.6.1.48 5-aminopentanoate + 2-oxoglutarate Anaerocolumna aminovalerica
-
 5-oxovalerate + L-glutamate
-
 r
2.6.1.48 5-aminopentanoate + 2-oxoglutarate Anaerocolumna aminovalerica T2-7
-
 5-oxovalerate + L-glutamate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.6.1.48 Anaerocolumna aminovalerica
-
 T2-7
-
2.6.1.48 Anaerocolumna aminovalerica T2-7
-
 T2-7
-
3.1.2.1 Anaerocolumna aminovalerica
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.6.1.48 partially Anaerocolumna aminovalerica

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.6.1.48 15.5
-
-
 Anaerocolumna aminovalerica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.6.1.48 4-aminobutyrate + 2-oxoglutarate
-
 Anaerocolumna aminovalerica succinic semialdehyde + L-glutamate
-
 r
2.6.1.48 4-aminobutyrate + 2-oxoglutarate
-
 Anaerocolumna aminovalerica T2-7 succinic semialdehyde + L-glutamate
-
 r
2.6.1.48 5-aminopentanoate + 2-oxoglutarate
-
 Anaerocolumna aminovalerica 5-oxovalerate + L-glutamate
-
 r
2.6.1.48 5-aminopentanoate + 2-oxoglutarate
-
 Anaerocolumna aminovalerica T2-7 5-oxovalerate + L-glutamate
-
 r
2.6.1.48 6-aminohexanoate + 2-oxoglutarate
-
 Anaerocolumna aminovalerica adipic semialdehyde + L-glutamate
-
 r
2.6.1.48 6-aminohexanoate + 2-oxoglutarate
-
 Anaerocolumna aminovalerica T2-7 adipic semialdehyde + L-glutamate
-
 r

Synonyms

EC Number Synonyms Comment Organism
3.1.2.1 acetyl-CoA thiol esterase
-
 Anaerocolumna aminovalerica

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.6.1.48 37
-
-
 Anaerocolumna aminovalerica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.6.1.48 8.2
-
 half-maximal rates at pH 6.5 and 9.8 Anaerocolumna aminovalerica

Cofactor

EC Number Cofactor Comment Organism Structure
2.6.1.48 pyridoxal 5'-phosphate
-
 Anaerocolumna aminovalerica