Literature summary extracted from

Klein, R.A.; Miller, P.G.G.; Linstead, D.J.
The enzymic hydrolysis of acetyl-coenzyme A by trypanosomatid flagellates (1976), Biochem. Soc. Trans., 4, 285-287.

Activating Compound

EC Number	Activating Compound	Comment	Organism	Structure
3.1.2.1	GDP	at 0.5 mM nucleoside phosphate 100% stimulation in Trypanosoma brucei brucei MIAG 103 and 75% in Trypanosoma brucei brucei 427	Trypanosoma brucei brucei
3.1.2.1	L(-)-carnitine	stimulation at 3mM	Crithidia fasciculata
3.1.2.1	L(-)-carnitine	stimulation at 3mM	Trypanosoma cruzi
3.1.2.1	L(-)-carnitine	stimulation at 3mM	Trypanosoma brucei brucei
3.1.2.1	L(-)-carnitine	stimulation at 3mM	Trypanosoma dionisii
3.1.2.1	L(-)-carnitine	stimulation at 3mM	Trypanosoma vespertilionis

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.1.2.1	ADP	0.5 mM nucleoside phosphate inhibits for 32% in Trypanosoma brucei brucei MIAG 103 and for 31% in Trypanosoma brucei brucei 427	Trypanosoma brucei brucei
3.1.2.1	ATP	0.5 mM nucleoside phosphate inhibits 49% in Trypanosoma brucei brucei 427	Trypanosoma brucei brucei

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.1.2.1	Crithidia fasciculata	-	-	-
3.1.2.1	Trypanosoma brucei brucei	-	-	-
3.1.2.1	Trypanosoma cruzi	-	-	-
3.1.2.1	Trypanosoma dionisii	-	-	-
3.1.2.1	Trypanosoma vespertilionis	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.1.2.1	flagellate	-	Crithidia fasciculata	-
3.1.2.1	flagellate	-	Trypanosoma cruzi	-
3.1.2.1	flagellate	-	Trypanosoma brucei brucei	-
3.1.2.1	flagellate	-	Trypanosoma dionisii	-
3.1.2.1	flagellate	-	Trypanosoma vespertilionis	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)