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Literature summary extracted from

  • Takematsu, H.; Diaz, S.; Stoddart, A.; Zhang, Y.; Varki, A.
    Lysosomal and cytosolic sialic acid 9-O-acetylesterase activities can be encoded by one gene via differential usage of a signal peptide-encoding exon at the N terminus (1999), J. Biol. Chem., 274, 25623-25631.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.53 endosome
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 Mus musculus 5768
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3.1.1.53 lysosome
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 Mus musculus 5764
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3.1.1.53 additional information the cytosolic and lysomomal form of the enzyme are found in very different subcellular compartments, but they are encoded by a single gene by different usage of a signal peptide-encoding exon at the N terminus Mus musculus
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Organism

EC Number Organism UniProt Comment Textmining
3.1.1.53 Mus musculus P70665
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-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.53 brain restricted distribution, strongest expression of the lysosomal enzyme Mus musculus
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3.1.1.53 liver restricted distribution, strongest expression of the lysosomal enzyme Mus musculus
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3.1.1.53 ovary restricted distribution, strongest expression of the lysosomal enzyme Mus musculus
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.53 N-acetyl-9-O-acetylneuraminate + H2O
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 Mus musculus N-acetylneuraminate + acetate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.1.53 cytosolic sialic acid 9-O-acetylesterase
-
 Mus musculus
3.1.1.53 lysosomal sialic acid 9-O-acetylesterase
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 Mus musculus