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Literature summary extracted from

  • Mirbod, F.; Banno, Y.; Ghannoum, M.A.; Ibrahim, A.S.; Nakashima, S.; Kitajima, Y.; Cole, G.T.; Nozawa, Y.
    Purification and characterization of lysophospholipase-transacylase (h-LPTA) from a highly virulant strain of Candida albicans (1995), Biochim. Biophys. Acta, 1257, 181-188.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.5 palmitoylcarnitine stimulates hydrolase activity Candida albicans

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.5 1-stearoyl-2-arachidonoyl-sn-glycero-3-phosphate
-
 Candida albicans
3.1.1.5 albumin
-
 Candida albicans
3.1.1.5 NEM transacylase activity Candida albicans
3.1.1.5 palmitoylcarnitine transacylase activity Candida albicans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.5 0.0606
-
 1-palmitoyl-sn-glycero-3-phosphocholine
-
 Candida albicans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.5 84000
-
 x * 84000, SDS-PAGE Candida albicans

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.5 Candida albicans
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.1.1.5 side-chain modification glycoprotein Candida albicans

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.5
-
 Candida albicans

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.5 117
-
 fatty acid release Candida albicans
3.1.1.5 459
-
 phosphatidylcholine formation Candida albicans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.5 1-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Candida albicans palmitic acid + glycero-3-phosphocholine
-
 ?
3.1.1.5 lysophosphatidylcholine + H2O
-
 Candida albicans glycerophosphorylcholine + unesterified fatty acid
-
 ?
3.1.1.5 lysophosphatidylcholine + lysophosphatidylcholine
-
 Candida albicans glycerophosphocholine + phosphatidylcholine
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.5 ? x * 84000, SDS-PAGE Candida albicans

Synonyms

EC Number Synonyms Comment Organism
3.1.1.5 h-LPTA
-
 Candida albicans
3.1.1.5 lysophospholipase-transacylase
-
 Candida albicans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.5 6
-
-
 Candida albicans

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.1.5 4 8 pH 4.0: about 65% of maximal activity, pH 8.0: about 40% of maximal activity, production of phosphatidylcholine Candida albicans