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Literature summary extracted from

  • Victoria, E.J.; Korn, E.D.
    Plasma membrane and soluble lysophospholipases of Acanthamoeba castellanii (1975), Arch. Biochem. Biophys., 171, 255-258.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.5 Triton X-100 stimulates membrane-bound enzyme Acanthamoeba castellanii

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.5 deoxycholate soluble enzyme Acanthamoeba castellanii
3.1.1.5 glutathione membrane-bound enzyme, no inhibition of the soluble enzyme Acanthamoeba castellanii
3.1.1.5 Hg2+
-
 Acanthamoeba castellanii
3.1.1.5 NEM soluble enzyme, no inhibition of the membrane-bound enzyme Acanthamoeba castellanii
3.1.1.5 SDS soluble and membrane-bound enzyme Acanthamoeba castellanii
3.1.1.5 Triton X-100 soluble enzyme Acanthamoeba castellanii
3.1.1.5 Zn2+
-
 Acanthamoeba castellanii

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.5 0.083
-
 lysophosphatidylcholine at low substrate concentrations Acanthamoeba castellanii
3.1.1.5 0.26
-
 lysophosphatidylcholine at high substrate concentrations Acanthamoeba castellanii

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.5 membrane
-
 Acanthamoeba castellanii 16020
-
3.1.1.5 plasma membrane
-
 Acanthamoeba castellanii 5886
-
3.1.1.5 soluble
-
 Acanthamoeba castellanii
-
-

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.5 Acanthamoeba castellanii
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.5 lysophosphatidylcholine + H2O
-
 Acanthamoeba castellanii glycerophosphorylcholine + unesterified fatty acid
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.5 6.5
-
 and a second optimum at pH 8.0, membrane-bound enzyme Acanthamoeba castellanii
3.1.1.5 7
-
 and a second optimum at pH 9.5, soluble enzyme Acanthamoeba castellanii
3.1.1.5 8
-
 and a second optimum at pH 6.5, membrane-bound enzyme Acanthamoeba castellanii
3.1.1.5 9.5
-
 and a second optimum at pH 7.0, soluble enzyme Acanthamoeba castellanii