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Literature summary extracted from

  • Fauvel, J.; Chap, H.; Roques, V.; Douste-Blazy, L.
    Substrate specificity of two cationic lipases with high phospholipase A1 activity purified from guinea pig pancreas. II. Studies on glycerophospholipids (1984), Biochim. Biophys. Acta, 792, 72-78.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.32 sodium deoxycholate activates Cavia porcellus

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.32 Cavia porcellus
-
 two cationic phospholipase A1 activities
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.32 pancreas
-
 Cavia porcellus
-

Storage Stability

EC Number Storage Stability Organism
3.1.1.32 -20°C, Tris-HCl buffer, pH 9.0, complete loss of activity after 1 month Cavia porcellus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.32 1-acyl-sn-glycero-3-phosphocholine + H2O
-
 Cavia porcellus fatty acid + glycero-3-phosphocholine
-
 ?
3.1.1.32 2-acyl-sn-glycero-3-phosphocholine + H2O
-
 Cavia porcellus fatty acid + glycerophosphocholine
-
 ?
3.1.1.32 additional information natural glycerophospholipids carrying a 1-acyl-bond are degraded in the following decreasing order of decreasing activity: phosphatidylcholine, phosphatidylinositol, 1-acyl-sn-glycero-3-phosphocholine, phosphatidylethanolamine, phosphatidylglycerol Cavia porcellus ?
-
 ?
3.1.1.32 additional information no activity with 1-alkyl-2-acyl-sn-glycero-3-phosphocholine Cavia porcellus ?
-
 ?
3.1.1.32 phosphatidylcholine + H2O
-
 Cavia porcellus ?
-
 ?
3.1.1.32 phosphatidylethanolamine + H2O
-
 Cavia porcellus ?
-
 ?
3.1.1.32 phosphatidylglycerol + H2O
-
 Cavia porcellus ?
-
 ?
3.1.1.32 phosphatidylinositol + H2O
-
 Cavia porcellus ?
-
 ?