EC Number | General Stability | Organism |
---|---|---|
3.1.1.25 | Ca2+, 1 mM, stabilizes | Homo sapiens |
3.1.1.25 | Ca2+, 1 mM, stabilizes | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.25 | Mg2+ | only inhibition of hydrolytic activity without affecting its lactonizing function | Homo sapiens | |
3.1.1.25 | Mg2+ | only inhibition of hydrolytic activity without affecting its lactonizing function | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.1.1.25 | 0.9 | - |
Gamma-caprolactone | - |
Homo sapiens | |
3.1.1.25 | 1.3 | - |
Gamma-octalactone | - |
Homo sapiens | |
3.1.1.25 | 2.2 | - |
Gamma-caprolactone | - |
Rattus norvegicus | |
3.1.1.25 | 3.1 | - |
Gamma-octalactone | - |
Rattus norvegicus | |
3.1.1.25 | 3.3 | - |
gamma-valerolactone | - |
Homo sapiens | |
3.1.1.25 | 4 | - |
gamma-valerolactone | - |
Rattus norvegicus | |
3.1.1.25 | 4.5 | - |
3-hydroxyoctanoate | - |
Homo sapiens | |
3.1.1.25 | 5.7 | - |
Gamma-hydroxycaproate | - |
Rattus norvegicus | |
3.1.1.25 | 6 | - |
gamma-butyrolactone | - |
Rattus norvegicus | |
3.1.1.25 | 9 | - |
Gamma-hydroxyvalerate | - |
Homo sapiens | |
3.1.1.25 | 10.4 | - |
Gamma-hydroxyvalerate | - |
Homo sapiens | |
3.1.1.25 | 13.3 | - |
gamma-butyrolactone | - |
Homo sapiens | |
3.1.1.25 | 20 | - |
Gamma-hydroxyvalerate | - |
Rattus norvegicus | |
3.1.1.25 | 140 | - |
gamma-hydroxybutyrate | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.1.25 | microsome | - |
Rattus norvegicus | - |
- |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
3.1.1.25 | Ca2+ | activates, hydrolysis is maximal at 0.01 mM , lactonization is maximal with 10 mM | Homo sapiens | |
3.1.1.25 | Ca2+ | activates, hydrolysis is maximal at 0.01 mM , lactonization is maximal with 10 mM | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.1.25 | Homo sapiens | - |
- |
- |
3.1.1.25 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.1.1.25 | blood plasma | - |
Homo sapiens | - |
3.1.1.25 | blood plasma | - |
Rattus norvegicus | - |
3.1.1.25 | liver | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.1.25 | 3-hydroxyoctanoate + H2O | - |
Homo sapiens | ? | - |
? | |
3.1.1.25 | gamma-butyrolactone + H2O | - |
Homo sapiens | gamma-hydroxybutyrate | - |
r | |
3.1.1.25 | gamma-butyrolactone + H2O | - |
Rattus norvegicus | gamma-hydroxybutyrate | - |
r | |
3.1.1.25 | gamma-caprolactone + H2O | - |
Homo sapiens | gamma-hydroxycaproate | - |
? | |
3.1.1.25 | gamma-caprolactone + H2O | - |
Rattus norvegicus | gamma-hydroxycaproate | - |
? | |
3.1.1.25 | gamma-octalactone + H2O | - |
Homo sapiens | 4-hydroxyoctanoate | - |
? | |
3.1.1.25 | gamma-octalactone + H2O | - |
Rattus norvegicus | 4-hydroxyoctanoate | - |
? | |
3.1.1.25 | gamma-valerolactone + H2O | - |
Homo sapiens | gamma-hydroxyvalerate | - |
? | |
3.1.1.25 | gamma-valerolactone + H2O | - |
Rattus norvegicus | gamma-hydroxyvalerate | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.1.1.25 | 6 | - |
- |
Homo sapiens |
3.1.1.25 | 6 | - |
- |
Rattus norvegicus |
3.1.1.25 | 8.6 | - |
- |
Homo sapiens |
3.1.1.25 | 8.6 | - |
- |
Rattus norvegicus |