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Literature summary extracted from
- Menaquinone (vitamin K2) biosynthesis: conversion of o-succinylbenzoic acid to 1,4-dihydroxy-2-naphthoic acid by Mycobacterium phlei enzymes (1979), J. Bacteriol., 140, 92-98.
General Stability
| EC Number | General Stability | Organism |
|---|---|---|
| 4.1.3.36 | DMSO stabilizes during purification | Mycolicibacterium phlei |
| 4.1.3.36 | unstable in the presence of ammonium sulfate | Mycolicibacterium phlei |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.36 | o-succinylbenzoyl-CoA | Mycolicibacterium phlei | pathway in menaquinone biosynthesis, i.e. vitamin K2, cf. EC 6.2.1.26 | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.1.3.36 | Mycolicibacterium phlei | - |
- |
- |
| 6.2.1.26 | Mycolicibacterium phlei | - |
- |
- |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.36 | additional information | - |
- |
Mycolicibacterium phlei |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.1.3.36 | o-succinylbenzoyl-CoA | - |
Mycolicibacterium phlei | 1,4-dihydroxy-2-naphthoyl-CoA + H2O | - |
? | |
| 4.1.3.36 | o-succinylbenzoyl-CoA | pathway in menaquinone biosynthesis, i.e. vitamin K2, cf. EC 6.2.1.26 | Mycolicibacterium phlei | ? | - |
? | |
| 6.2.1.26 | ATP + 2-succinylbenzoate + CoA | - |
Mycolicibacterium phlei | AMP + diphosphate + 2-succinylbenzoyl-CoA | the o-succinylbenzoyl-CoA derivative is rather unstable, under a variety of conditions it is converted to a spirodilactone form of o-succinylbenzoate | ? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.1.3.36 | dihydroxynaphthoate synthase | - |
Mycolicibacterium phlei |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 4.1.3.36 | 30 | - |
assay at | Mycolicibacterium phlei |
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