EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.7 | EDTA | - |
Rattus norvegicus |
EC Number | Metals/Ions | Comment | Organism | Structure |
---|---|---|---|---|
6.2.1.7 | Mg2+ | stimulates up to a maximal concentration of 5 mM | Rattus norvegicus |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.7 | ATP + cholate + CoA | Rattus norvegicus | kidney has the potential for bile acid metabolism and may have a role in bile acid physiology. Conjugation of bile acids in the kidney may serve as a protective mechanism by which the renal cell avoids injury from circulating unconjugated bile acids | AMP + diphosphate + choloyl-CoA | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
6.2.1.7 | Rattus norvegicus | - |
- |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
6.2.1.7 | kidney | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
6.2.1.7 | ATP + chenodeoxycholate + CoA | - |
Rattus norvegicus | AMP + diphosphate + chenodeoxycholoyl-CoA | - |
? | |
6.2.1.7 | ATP + cholate + CoA | kidney has the potential for bile acid metabolism and may have a role in bile acid physiology. Conjugation of bile acids in the kidney may serve as a protective mechanism by which the renal cell avoids injury from circulating unconjugated bile acids | Rattus norvegicus | AMP + diphosphate + choloyl-CoA | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
6.2.1.7 | 8.5 | - |
- |
Rattus norvegicus |
EC Number | pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|---|
6.2.1.7 | 6.5 | 9.8 | 6.5: about 30% of maximal activity, 9.8: about 50% of maximal activity | Rattus norvegicus |