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Literature summary extracted from
- Kinetics of blood coagulation factor Xaalpha autoproteolytic conversion to factor Xabeta. Effect on inhibition by antithrombin, prothrombinase assembly, and enzyme activity (1996), J. Biol. Chem., 271, 16621-16626.
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.6 | prothrombin + H2O | Bos taurus | factor Xaalpha is predominantly responsible for thrombin generation. Slow conversion to factor Xabeta coordinates coagulation and the initiation of fibrinolysis at sites of thrombinase assembly | ? | - |
? |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.21.6 | Bos taurus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.21.6 | proteolytic modification | autoproteolytic conversion of factor Xaalpha to factor Xabeta by excision of a 4000 Da fragment, beta-peptide | Bos taurus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.21.6 | prothrombin + H2O | factor Xaalpha is predominantly responsible for thrombin generation. Slow conversion to factor Xabeta coordinates coagulation and the initiation of fibrinolysis at sites of thrombinase assembly | Bos taurus | ? | - |
? | |
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