Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fricker, L.D.; Snyder, S.H.
    Purification and characterization of enkephalin convertase, an enkephalin-synthesizing carboxypeptidase (1983), J. Biol. Chem., 258, 10950-10955.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.17.10 Guanidinoethylmercaptosuccinic acid
-
 Bos taurus
3.4.17.10 [Leu5]Enkephalin-Arg6
-
 Bos taurus
3.4.17.10 [Met5]Enkephalin-Arg6
-
 Bos taurus
3.4.17.10 [Met5]Enkephalin-Lys6
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.17.10 0.018
-
 dansyl-Phe-Ala-Arg pituitary Bos taurus
3.4.17.10 0.019
-
 dansyl-Phe-Ala-Arg adrenal Bos taurus
3.4.17.10 0.022
-
 dansyl-Phe-Ala-Arg brain Bos taurus
3.4.17.10 0.029 0.031 dansyl-Phe-Gly-Arg
-
 Bos taurus
3.4.17.10 0.058 0.062 Dansyl-Pro-Ala-Arg
-
 Bos taurus
3.4.17.10 0.066 0.071 dansyl-Phe-Leu-Arg
-
 Bos taurus
3.4.17.10 0.068 0.077 dansyl-Phe-Ile-Arg
-
 Bos taurus
3.4.17.10 0.1 0.12 Dansyl-Ala-Arg
-
 Bos taurus
3.4.17.10 0.16 0.18 dansyl-Phe-Leu-Gly-Arg
-
 Bos taurus
3.4.17.10 0.34 0.49 dansyl-Phe-Leu-Ala-Arg
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.17.10 secretory granule chromaffin granules Bos taurus 30141
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.17.10 50000
-
 non-denaturing PAGE, gel filtration Bos taurus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.17.10 additional information Bos taurus
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.10 Bos taurus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.17.10
-
 Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.10 adrenal medulla
-
 Bos taurus
-
3.4.17.10 brain
-
 Bos taurus
-
3.4.17.10 hypophysis
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.17.10 120
-
-
 Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.10 Dansyl-Ala-Arg + H2O
-
 Bos taurus Dansyl-Ala + Arg
-
 ?
3.4.17.10 Dansyl-Phe-Ala-Arg + H2O
-
 Bos taurus Dansyl-Phe-Ala + Arg
-
 ?
3.4.17.10 Dansyl-Phe-Gly-Arg + H2O
-
 Bos taurus Dansyl-Phe-Gly + Arg
-
 ?
3.4.17.10 Dansyl-Phe-Ile-Arg + H2O
-
 Bos taurus Dansyl-Phe-Ile + Arg
-
 ?
3.4.17.10 dansyl-Phe-Leu-Ala-Arg + H2O
-
 Bos taurus dansyl-Phe-Leu-Ala + Arg
-
 ?
3.4.17.10 Dansyl-Phe-Leu-Arg + H2O
-
 Bos taurus Dansyl-Phe-Leu + Arg
-
 ?
3.4.17.10 dansyl-Phe-Leu-Gly-Arg + H2O
-
 Bos taurus dansyl-Phe-Leu-Gly + Arg
-
 ?
3.4.17.10 Dansyl-Pro-Ala-Arg + H2O
-
 Bos taurus Dansyl-Pro-Ala + Arg
-
 ?
3.4.17.10 enkephalin precursor + H2O
-
 Bos taurus ?
-
 ?
3.4.17.10 additional information
-
 Bos taurus ?
-
 ?
3.4.17.10 proinsulin tryptic peptides + H2O
-
 Bos taurus ?
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.4.17.10 5 6
-
 Bos taurus