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Literature summary extracted from
- Microbial synthesis of metabolites with antihypertensive activity: aspects of fermentation derived inhibitors of angiotensin-converting enzyme (ACE) (1989), J. Basic Microbiol., 29, 623-639.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.15.1 | 15 B1 | - |
Homo sapiens |  |
| 3.4.15.1 | 15 B2 | - |
Homo sapiens | |
| 3.4.15.1 | A 58365A | - |
Homo sapiens | |
| 3.4.15.1 | A 58365B | - |
Homo sapiens | |
| 3.4.15.1 | ancovenin | - |
Homo sapiens | |
| 3.4.15.1 | aspergillomarasmine A | - |
Homo sapiens | |
| 3.4.15.1 | aspergillomarasmine B | - |
Homo sapiens | |
| 3.4.15.1 | foroxymithine | - |
Homo sapiens | |
| 3.4.15.1 | K-13 | - |
Homo sapiens | |
| 3.4.15.1 | K-26 | - |
Homo sapiens | |
| 3.4.15.1 | K-4 | - |
Homo sapiens | |
| 3.4.15.1 | L-681,176 | - |
Homo sapiens | |
| 3.4.15.1 | muracein A | - |
Homo sapiens | |
| 3.4.15.1 | muracein B | - |
Homo sapiens | |
| 3.4.15.1 | muracein C | - |
Homo sapiens | |
| 3.4.15.1 | phenacein | - |
Homo sapiens | |
| 3.4.15.1 | talopeptin | - |
Homo sapiens | |
| 3.4.15.1 | WF-10,129 | - |
Homo sapiens | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.15.1 | additional information | Homo sapiens | plays a role in blood pressure regulation | ? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.15.1 | brain | - |
Homo sapiens | - |
| 3.4.15.1 | kidney | - |
Homo sapiens | - |
| 3.4.15.1 | lung | - |
Homo sapiens | - |
| 3.4.15.1 | testis | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.15.1 | furanacryloyl-L-Phe-Gly-Gly + H2O | - |
Homo sapiens | furanacryloyl-L-Phe + Gly-Gly | - |
? | |
| 3.4.15.1 | hippuryl-His-Leu + H2O | - |
Homo sapiens | hippuric acid + His-Leu | - |
? | |
| 3.4.15.1 | additional information | plays a role in blood pressure regulation | Homo sapiens | ? | - |
? | |
| 3.4.15.1 | p-nitrobenzyloxycarbonyl-Gly + H2O | - |
Homo sapiens | ? | - |
? | |
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