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Literature summary extracted from

  • Kalinina, E.V.; Posdnev, V.F.; Komissarova, N.V.; Gomazkov, O.A.
    Effect of new peptide inhibitors on the ratio of angiotensin I-converting and kinin-degrading activities of dipeptidyl carboxypeptidase (angiotensin-converting enzyme) (1997), Biochemistry, 62, 247-250.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 benzoyl-NHCOCH2CH(COOH)-Ala-Pro-OH
-
 Rattus norvegicus
3.4.15.1 benzoyl-NHCOCH2CH(COOH)-Trp-Pro-OH
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.15.1 0.5
-
 hippuryl-Phe-Arg heart enzyme Rattus norvegicus
3.4.15.1 0.7
-
 hippuryl-Phe-Arg lung enzyme Rattus norvegicus
3.4.15.1 1.2
-
 hippuryl-His-Leu lung enzyme Rattus norvegicus
3.4.15.1 1.8
-
 hippuryl-His-Leu kidney enzyme Rattus norvegicus
3.4.15.1 1.8
-
 hippuryl-Phe-Arg kidney enzyme Rattus norvegicus
3.4.15.1 4
-
 hippuryl-His-Leu heart enzyme Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 heart
-
 Rattus norvegicus
-
3.4.15.1 kidney
-
 Rattus norvegicus
-
3.4.15.1 lung
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 hippuryl-His-Leu + H2O
-
 Rattus norvegicus hippuric acid + His-Leu
-
 ?
3.4.15.1 hippuryl-Phe-Arg + H2O
-
 Rattus norvegicus hippuric acid + Phe-Arg
-
 ?