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Literature summary extracted from

  • Dorer, F.E.; Kahn, J.R.; Lentz, K.E.; Levine, M.; Skeggs, L.T.
    Kinetic properties of pulmonary angiotensin-converting enzyme. Hydrolysis of hippurylglycylglycine (1976), Biochim. Biophys. Acta, 429, 220-228.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.4.15.1 Cl-
-
 Sus scrofa

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 Arg-Pro-Pro more inhibitory at pH 8 than at pH 6 Sus scrofa
3.4.15.1 EDTA somewhat more effective at pH 6 than at pH 8 Sus scrofa
3.4.15.1 Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro
-
 Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.4.15.1 0.9
-
 hippuryl-Gly-Gly pH 6, 0.1 M NaCl Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.4.15.1 Co2+ activation Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Sus scrofa
-
 hog
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 lung
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 hippuryl-Gly-Gly + H2O
-
 Sus scrofa hippuric acid + Gly-Gly
-
 ?