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Literature summary extracted from

  • Lanzillo, J.J.; Stevens, J.; Dasarathy, Y.; Yotsumoto, H.; Fanburg, B.L.
    Angiotensin-converting enzyme from human tissues. Physicochemical, catalytic, and immunological properties (1985), J. Biol. Chem., 260, 14938-14944.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.4.15.1 captopril
-
 Homo sapiens
3.4.15.1 EDTA
-
 Homo sapiens
3.4.15.1 lisinopril
-
 Homo sapiens

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.15.1 membrane membrane-bound Homo sapiens 16020
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.4.15.1 140000
-
 lung, kidney, blood plasma, seminal plasma, two testicular enzyme forms of MW 90000 Da and 140000 Da are detected, gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.15.1 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.4.15.1
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.15.1 kidney
-
 Homo sapiens
-
3.4.15.1 lung
-
 Homo sapiens
-
3.4.15.1 plasma
-
 Homo sapiens
-
3.4.15.1 semen seminal plasma Homo sapiens
-
3.4.15.1 testis
-
 Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.4.15.1 additional information
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.15.1 angiotensin I + H2O
-
 Homo sapiens angiotensin II + His-Leu
-
 ?
3.4.15.1 Gly-Gly-Tyr-Arg + H2O
-
 Homo sapiens Gly-Gly + Tyr-Arg
-
 ?
3.4.15.1 hippuryl-His-Leu + H2O
-
 Homo sapiens hippuric acid + His-Leu
-
 ?
3.4.15.1 Met5-enkephalin + H2O
-
 Homo sapiens Tyr-Gly-Gly + Phe-Met
-
 ?