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Literature summary extracted from

  • Shetty, V.; Shetty, K.T.
    Phosphoserine phosphatase of human brain: partial purification, characterization, regional distribution, and effect of certain modulators including psychoactive drugs (1991), Neurochem. Res., 16, 1203-1210.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.3.3 Chlordiazepoxide activation Homo sapiens
3.1.3.3 diazepam activation Homo sapiens
3.1.3.3 sucrose activation Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.3.3 Ca2+
-
 Homo sapiens
3.1.3.3 chlorpromazine
-
 Homo sapiens
3.1.3.3 F-
-
 Homo sapiens
3.1.3.3 Mn2+
-
 Homo sapiens
3.1.3.3 Trifluorperazine
-
 Homo sapiens
3.1.3.3 vanadate
-
 Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.3.3 0.036
-
 L-phosphoserine
-
 Homo sapiens
3.1.3.3 0.1
-
 D-phosphoserine
-
 Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.3 Cu2+ activation Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.3 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.3.3 partially Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.3.3 brain cortex, brain stem, cerebellum, striatum, thalamus hippocampus Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.3 beta-glycerophosphate + H2O
-
 Homo sapiens glycerol + phosphate
-
 ?
3.1.3.3 D-fructose 6-phosphate + H2O
-
 Homo sapiens D-fructose + phosphate
-
 ?
3.1.3.3 D-phosphoserine + H2O
-
 Homo sapiens D-Ser + phosphate
-
 ?
3.1.3.3 L-phosphoserine + H2O
-
 Homo sapiens L-Ser + phosphate
-
 ?
3.1.3.3 O-phospho-L-tyrosine + H2O
-
 Homo sapiens L-Tyr + phosphate
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.3.3 5.6 6.6
-
 Homo sapiens