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Literature summary extracted from

  • Koivusalo, M.; Lapatto, R.; Uotila, L.
    Purification and characterization of S-formylglutathione hydrolase from human, rat and fish tissues (1995), Adv. Exp. Med. Biol., 372, 427-434.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.2.12 0.019
-
 4-methylumbelliferyl acetate
-
 Homo sapiens
3.1.2.12 0.2
-
 S-formylglutathione
-
 Homo sapiens
3.1.2.12 0.49
-
 4-nitrophenyl acetate
-
 Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.2.12 32000
-
 2 * 32000, SDS-PAGE Homo sapiens
3.1.2.12 53000
-
 gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.1.2.12 Homo sapiens
-
-
-
3.1.2.12 Lota maculosa
-
 burbot
-
3.1.2.12 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.2.12
-
 Homo sapiens
3.1.2.12 partial Rattus norvegicus
3.1.2.12 partial Lota maculosa

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.2.12 erythrocyte
-
 Homo sapiens
-
3.1.2.12 liver
-
 Homo sapiens
-
3.1.2.12 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.2.12 26.9
-
-
 Lota maculosa
3.1.2.12 208
-
-
 Rattus norvegicus
3.1.2.12 3390
-
-
 Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.2.12 4-methylumbelliferyl acetate + H2O
-
 Homo sapiens 4-methylumbelliferone + acetate
-
 ?
3.1.2.12 4-methylumbelliferyl acetate + H2O very low activity Rattus norvegicus 4-methylumbelliferone + acetate
-
 ?
3.1.2.12 4-methylumbelliferyl acetate + H2O very low activity Lota maculosa 4-methylumbelliferone + acetate
-
 ?
3.1.2.12 4-nitrophenyl acetate + H2O
-
 Homo sapiens 4-nitrophenol + acetate
-
 ?
3.1.2.12 p-nitrophenyl acetate + H2O very low activity Rattus norvegicus p-nitrophenol + acetate
-
 ?
3.1.2.12 p-nitrophenyl acetate + H2O very low activity Lota maculosa p-nitrophenol + acetate
-
 ?
3.1.2.12 S-acetylglutathione + H2O
-
 Homo sapiens glutathione + acetate
-
 ?
3.1.2.12 S-acetylglutathione + H2O
-
 Rattus norvegicus glutathione + acetate
-
 ?
3.1.2.12 S-acetylglutathione + H2O
-
 Lota maculosa glutathione + acetate
-
 ?
3.1.2.12 S-formylglutathione + H2O
-
 Homo sapiens glutathione + formate
-
 ?
3.1.2.12 S-formylglutathione + H2O
-
 Rattus norvegicus glutathione + formate
-
 ?
3.1.2.12 S-formylglutathione + H2O
-
 Lota maculosa glutathione + formate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.2.12 dimer 2 * 32000, SDS-PAGE Homo sapiens