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Literature summary extracted from

  • Grigg, M.E.; Gounaris, K.; Selkirk, M.E.
    Characterization of a platelet-activating factor acetylhydrolase secreted by the nematode parasite Nippostrongylus brasiliensis (1996), Biochem. J., 317, 541-547.
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.47 1-O-alkyl-2-propionyl-sn-glycero-3-phosphocholine
-
 Nippostrongylus brasiliensis
3.1.1.47 1-O-hexadecyl-2-thioacetyl-sn-glycero-3-phosphocholine
-
 Nippostrongylus brasiliensis
3.1.1.47 diisopropylfluorophosphate slightly inhibitory Nippostrongylus brasiliensis
3.1.1.47 phenylmethylsulfonyl fluoride
-
 Nippostrongylus brasiliensis

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.47 Ca2+ 1 mM CaCl2 required for maximal hydrolysis Nippostrongylus brasiliensis

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.47 25000
-
 1 * 38000 + 1 * 25000, SDS-PAGE Nippostrongylus brasiliensis
3.1.1.47 38000
-
 1 * 38000 + 1 * 25000, SDS-PAGE Nippostrongylus brasiliensis
3.1.1.47 64000
-
 gel filtration Nippostrongylus brasiliensis

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.47 Nippostrongylus brasiliensis
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.47
-
 Nippostrongylus brasiliensis

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O
-
 Nippostrongylus brasiliensis 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.47 dimer 1 * 38000 + 1 * 25000, SDS-PAGE Nippostrongylus brasiliensis