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Literature summary extracted from

  • Blank, M.L.; Lee, T.; Fitzgerald, V.; Snyder, F.
    A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid) (1981), J. Biol. Chem., 256, 175-178.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.47 1-Alkyl-2,3-diacetyl-sn-glycerol slight Rattus norvegicus
3.1.1.47 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphoethanolamine
-
 Rattus norvegicus
3.1.1.47 2-acetyl-1-acyl-glycero-sn-glycero-3-phosphocholine
-
 Rattus norvegicus
3.1.1.47 3-Hexadecyl-2-acetyl-sn-glycero-1-phosphocholine
-
 Rattus norvegicus
3.1.1.47 deoxycholate
-
 Rattus norvegicus
3.1.1.47 diisopropylfluorophosphate
-
 Rattus norvegicus
3.1.1.47 phosphatidylcholine from egg, long chain diacetyl type, slight Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.47 0.0031
-
 1-hexadecyl-2-acetyl-sn-glycerol-3-phosphocholine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.1.1.47 cytoplasm
-
 Rattus norvegicus 5737
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.47 additional information no stimulation by Ca2+ or Mg2+ Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O Rattus norvegicus i.e. PAF ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.47 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.47 brain
-
 Rattus norvegicus
-
3.1.1.47 heart
-
 Rattus norvegicus
-
3.1.1.47 kidney
-
 Rattus norvegicus
-
3.1.1.47 liver
-
 Rattus norvegicus
-
3.1.1.47 lung
-
 Rattus norvegicus
-
3.1.1.47 plasma
-
 Rattus norvegicus
-
3.1.1.47 spleen
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.47 0.0031
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.47 1-hexadecyl-2-acetyl-sn-glycerol-3-phosphocholine + H2O i.e. PAF Rattus norvegicus 1-hexadecyl-sn-glycerol-3-phosphocholine + acetate
-
 ?
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O i.e. PAF Rattus norvegicus 1-O-alkyl-sn-glycero-3-phosphocholine + acetate
-
 ?
3.1.1.47 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O i.e. PAF Rattus norvegicus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.1.1.47 37
-
 enzyme assay Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.47 7.5 8.5
-
 Rattus norvegicus