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Literature summary extracted from

  • Militello, K.T.; Finnerty-Haggerty, L.; Kambhampati, O.; Huss, R.; Knapp, R.
    DNA cytosine methyltransferase enhances viability during prolonged stationary phase in Escherichia coli (2020), FEMS Microbiol. Lett., 367, fnaa166.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.37 Escherichia coli
-
-
-
2.1.1.37 Escherichia coli BW25113
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.37 S-adenosyl-L-methionine + DNA containing 5'CCWGG3'
-
 Escherichia coli S-adenosyl-L-homocysteine + DNA containing 5'CCWGG3' containing 5-methylcytosine
-
 ?
2.1.1.37 S-adenosyl-L-methionine + DNA containing 5'CCWGG3'
-
 Escherichia coli BW25113 S-adenosyl-L-homocysteine + DNA containing 5'CCWGG3' containing 5-methylcytosine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.1.1.37 DCM
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
2.1.1.37 physiological function no growth defect is associated with loss of cytosine DNA methylation under standard laboratory conditions, low-temperature stress conditions, and nutrient limitation conditions. Presence of Dcm positively impacts prolonged stationary phase, and cells lacking Dcm activity have increased total catalase activity compared to wild-type Escherichia coli