Any feedback?
Literature summary extracted from
- Search for inhibitors of Mycobacterium tuberculosis transketolase in a series of sulfo-substituted compounds (2023), Acta naturae, 15, 81-83.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 2.2.1.1 | 5-[(E)-(2-[[(5,8-dihydronaphthalen-1-yl)amino]acetyl]hydrazinylidene)methyl]furan-2-sulfonic acid | compound competes for the binding site of the diphosphate group of the thiamine diphosphate cofactor and is able to suppress the activity of mycobacterial transketolase at micromolar concentrations | Mycobacterium tuberculosis |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 2.2.1.1 | Mycobacterium tuberculosis | P9WG25 | - |
- |
| 2.2.1.1 | Mycobacterium tuberculosis H37Rv | P9WG25 | - |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 2.2.1.1 | Rv1449c | - |
Mycobacterium tuberculosis |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2026.1 (March 2026)
Legal
Curated at
Member of
![DSMZ Digital Diversity]()
![Global Core Biodata Resource]()
![ELIXIR Core Data Resource]()
![German Network for Bioinformatics Infrastructure]()
