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Literature summary extracted from

  • Stierle, S.A.; Harken, L.; Li, S.M.
    Production of diketopiperazine derivatives by pathway engineering with different cyclodipeptide synthases from various Streptomyces strains (2023), ACS Synth. Biol., 12, 1804-1812.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.2.B23 synthesis expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides Streptomyces monomycini
2.3.2.B23 synthesis expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides Streptomyces varsoviensis
2.3.2.B23 synthesis expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides Streptomyces sp. NRRL F-5053
2.3.2.B23 synthesis expression of CDPS and genes gtmB-gtmE for tailoring enzymes from Streptomyces cinnamoneus enables the synthesis of modified cyclodipeptides Streptomyces sp. NRRL S-1868

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.B23 Streptomyces monomycini
-
-
-
2.3.2.B23 Streptomyces monomycini NRRL B-24309
-
-
-
2.3.2.B23 Streptomyces sp. NRRL F-5053
-
-
-
2.3.2.B23 Streptomyces sp. NRRL S-1868
-
-
-
2.3.2.B23 Streptomyces varsoviensis
-
-
-
2.3.2.B23 Streptomyces varsoviensis NRRL B-3589
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.B23 L-tryptophanyl-tRNATrp + L-alanyl-tRNAAla
-
 Streptomyces sp. NRRL S-1868 tRNATrp + tRNAAla + cyclo(L-tryptophanyl-L-alanyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-leucyl-tRNALeu
-
 Streptomyces sp. NRRL F-5053 tRNATrp + tRNALeu + cyclo(L-tryptophanyl-L-leucyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe
-
 Streptomyces monomycini tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe
-
 Streptomyces varsoviensis tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe
-
 Streptomyces monomycini NRRL B-24309 tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-phenylalanyl-tRNAPhe
-
 Streptomyces varsoviensis NRRL B-3589 tRNATrp + tRNAPhe + cyclo(L-tryptophanyl-L-phenylalanyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-prolyl-tRNAPro
-
 Streptomyces sp. NRRL S-1868 tRNATrp + tRNAPro + cyclo(L-tryptophanyl-L-prolyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-tyrosyl-tRNATyr
-
 Streptomyces varsoviensis tRNATrp + tRNATyr + cyclo(L-tryptophanyl-L-tyrosyl)
-
 ?
2.3.2.B23 L-tryptophanyl-tRNATrp + L-tyrosyl-tRNATyr
-
 Streptomyces varsoviensis NRRL B-3589 tRNATrp + tRNATyr + cyclo(L-tryptophanyl-L-tyrosyl)
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.2.B23 ASPA
-
 Streptomyces sp. NRRL S-1868
2.3.2.B23 CWLS1
-
 Streptomyces sp. NRRL F-5053
2.3.2.B23 GutA24309
-
 Streptomyces monomycini
2.3.2.B23 GutA3589
-
 Streptomyces varsoviensis
2.3.2.B23 NasA
-
 Streptomyces sp. NRRL S-1868