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Literature summary extracted from
- Mechanistic analysis of A46V, H57Y, and D129N in pyrazinamidase associated with pyrazinamide resistance (2020), Saudi J. Biol. Sci., 27, 3150-3156.
Protein Variants
| EC Number | Protein Variants | Comment | Organism |
|---|---|---|---|
| 3.5.1.B15 | A46V | mutation confers resistance to pyrazinamide. The RMSD and RMSF values are elecated compared to wild-type | Mycobacterium tuberculosis |
| 3.5.1.B15 | D129N | mutation confers resistance to pyrazinamide. The RMSD and RMSF values are elecated compared to wild-type | Mycobacterium tuberculosis |
| 3.5.1.B15 | H57Y | mutation confers resistance to pyrazinamide. The RMSD and RMSF values are elecated compared to wild-type | Mycobacterium tuberculosis |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.5.1.B15 | Mycobacterium tuberculosis | I6XD65 | cf. EC 3.5.1.19 | - |
| 3.5.1.B15 | Mycobacterium tuberculosis H37Rv | I6XD65 | cf. EC 3.5.1.19 | - |
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Release 2026.1 (March 2026)
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