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Literature summary extracted from

  • Huang, L.; Khusnutdinova, A.; Nocek, B.; Brown, G.; Xu, X.; Cui, H.; Petit, P.; Flick, R.; Zallot, R.; Balmant, K.; Ziemak, M.; Shanklin, J.; De Crecy-Lagard, V.; Fiehn, O.; Gregory, J.; Joachimiak, A.; Savchenko, A.; Yakunin, A.; Hanson, A.
    A family of metal-dependent phosphatases implicated in metabolite damage-control (2016), Nat. Chem. Biol., 12, 621-627.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.1.3.110 expressed in Escherichia coli Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.3.110 Co2+ 0.5 mM used in assay conditions Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.110 4'-phosphopantetheine + H2O Homo sapiens
-
 pantetheine + phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.3.110 Homo sapiens
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.3.110 2',5'-ADP + H2O
-
 Homo sapiens 2',5'-AMP + phosphate
-
 ?
3.1.3.110 4'-phosphopantetheine + H2O
-
 Homo sapiens pantetheine + phosphate
-
 ?
3.1.3.110 4-nitrophenyl diphosphate + H2O highest activity Homo sapiens 4-nitrophenyl phosphate + phosphate
-
 ?
3.1.3.110 D-galactose 1'-phosphate + H2O lowest activity Homo sapiens D-galactose + phosphate
-
 ?
3.1.3.110 D-glucose 6'-phosphate + H2O
-
 Homo sapiens D-glucose + phosphate
-
 ?
3.1.3.110 glycine phosphate + H2O
-
 Homo sapiens glycine + phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.3.110 PanK4
-
 Homo sapiens
3.1.3.110 pantothenate kinase 4
-
 Homo sapiens