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Literature summary extracted from

  • Jain, A.; Correia, M.S.P.; Meistermann, H.; Vujasinovic, M.; Loehr, J.M.; Globisch, D.
    Comparison of two arylsulfatases for targeted mass spectrometric analysis of microbiota-derived metabolites (2021), J. Pharm. Biomed. Anal., 195, 113818.
    View publication on PubMed

Application

EC Number Application Comment Organism
3.1.6.1 diagnostics selective identification of organic sulfate esters in human urine samples. Arylsulfatase ASPC can also be utilized for large-scale analysis and discovery of sulfated metabolites and does not require purification prior to application Helix pomatia

Organism

EC Number Organism UniProt Comment Textmining
3.1.6.1 Helix pomatia
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.6.1 2-(1-hydroxypenta-2,4-dien-2-yl)-4-methoxyphenol sulfate 75.3% hydrolysis by arylsulfatase ASPC Helix pomatia 2-(1-hydroxypenta-2,4-dien-2-yl)-4-methoxyphenol + sulfate
-
 ?
3.1.6.1 2-aminophenol sulfate + H2O less than 20% hydrolysis by arylsulfatase ASPC, nohydrolysis by arylsulfatase Hp-AS Helix pomatia 2-aminophenol + sulfate
-
 ?
3.1.6.1 2-biphenylol sulfate + H2O 37.9% hydrolysis by arylsulfatase ASPC Helix pomatia 2-biphenylol + sulfate
-
 ?
3.1.6.1 2-tert-butylhydroquinone sulfate + H2O 88.6% hydrolysis by arylsulfatase ASPC Helix pomatia 2-tert-butylhydroquinone + sulfate
-
 ?
3.1.6.1 3-hydroxy-2-methyl-4-pyrone sulfate 34.6% hydrolysis by arylsulfatase ASPC Helix pomatia 3-hydroxy-2-methyl-4-pyrone + sulfate
-
 ?
3.1.6.1 3-hydroxy-5-methylphenyl sulfate + H2O 93.5% hydrolysis by arylsulfatase ASPC Helix pomatia 3-hydroxy-5-methylphenyl + sulfate
-
 ?
3.1.6.1 3-methoxy-4-hydroxyphenylglycol sulfate + H2O 84.3% hydrolysis by arylsulfatase ASPC Helix pomatia 3-methoxy-4-hydroxyphenylglycol + sulfate
-
 ?
3.1.6.1 3-methoxyphenol sulfate + H2O 96.6% hydrolysis by arylsulfatase ASPC Helix pomatia 3-methoxyphenol + sulfate
-
 ?
3.1.6.1 4-(3-hydroxyphenyl)-4-oxobut-2-enoic acid sulfate 39.0% hydrolysis by arylsulfatase ASPC Helix pomatia 4-(3-hydroxyphenyl)-4-oxobut-2-enoic acid + sulfate
-
 ?
3.1.6.1 4-aminophenol sulfate + H2O 5% hydrolysis by arylsulfatase ASPC, 23.3% hydrolysis by arylsulfatase Hp-AS Helix pomatia 4-aminophenol + sulfate
-
 ?
3.1.6.1 4-hydroxy-3-methylanisol + H2O 82.5% hydrolysis by arylsulfatase ASPC Helix pomatia 4-hydroxy-3-methylanisol + sulfate
-
 ?
3.1.6.1 4-hydroxyacetaminophen sulfate + H2O 98.9% hydrolysis by arylsulfatase ASPC Helix pomatia 4-hydroxyacetaminophen + sulfate
-
 ?
3.1.6.1 4-methylumbelliferyl sulfate + H2O 100% hydrolysis by arylsulfatase ASPC, 100% hydrolysis by arylsulfatase Hp-AS Helix pomatia 4-methylumbelliferone + sulfate
-
 ?
3.1.6.1 5,6-dihydroxycyclohexa-1,3-dien-1-yl sulfate 99.7% hydrolysis by arylsulfatase ASPC Helix pomatia 5,6-dihydroxycyclohexa-1,3-dien-1-ol + sulfate
-
 ?
3.1.6.1 5-methylcytosine sulfate + H2O 92.8% hydrolysis by arylsulfatase ASPC Helix pomatia 5-methylcytosine + sulfate
-
 ?
3.1.6.1 6-hydroxycyclohexa-1,3-dien-yl sulfate 92.0% hydrolysis by arylsulfatase ASPC Helix pomatia 6-hydroxycyclohexa-1,3-dien-ol + sulfate
-
 ?
3.1.6.1 ascorbic acid-2-sulfate 91.3% hydrolysis by arylsulfatase ASPC Helix pomatia ascorbic acid + sulfate
-
 ?
3.1.6.1 D-mannose-6-sulfate + H2O 42% hydrolysis by arylsulfatase ASPC, less than 20% hydrolysis by arylsulfatase Hp-AS Helix pomatia D-mannose + sulfate
-
 ?
3.1.6.1 dihydroisoandrosterone-3-sulfate 91.5% hydrolysis by arylsulfatase ASPC Helix pomatia dihydroisoandrosterone + sulfate
-
 ?
3.1.6.1 dihydroisoandrosterone-3-sulfate + H2O no hydrolysis by arylsulfatase ASPC, 38% hydrolysis by arylsulfatase Hp-AS Helix pomatia dihydroisoandrosterone + sulfate
-
 ?
3.1.6.1 estrone-3-sulfate + H2O 100% hydrolysis by arylsulfatase ASPC, 100% hydrolysis by arylsulfatase Hp-AS Helix pomatia estrone + sulfate
-
 ?
3.1.6.1 hesperetin sulfate + H2O 88.9% hydrolysis by arylsulfatase ASPC Helix pomatia hesperetin + sulfate
-
 ?
3.1.6.1 homovanillic acid sulfate 93.2% hydrolysis by arylsulfatase ASPC Helix pomatia homovanillic acid + sulfate
-
 ?
3.1.6.1 isoferulic acid sulfate + H2O 95.0% hydrolysis by arylsulfatase ASPC Helix pomatia isoferulic acid + sulfate
-
 ?
3.1.6.1 L-tyrosine sulfate + H2O less than 20% hydrolysis by arylsulfatase ASPC, less than 20% hydrolysis by arylsulfatase Hp-AS Helix pomatia L-tyrosine + sulfate
-
 ?
3.1.6.1 methylurolithin sulfate + H2O 100% hydrolysis by arylsulfatase ASPC, 100% hydrolysis by arylsulfatase Hp-AS Helix pomatia methylurolithin + sulfate
-
 ?
3.1.6.1 N-acetylserotonin sulfate + H2O 100% hydrolysis by arylsulfatase ASPC, no hydrolysis by arylsulfatase Hp-AS Helix pomatia N-acetylserotonin + sulfate
-
 ?
3.1.6.1 N-acetyltyramine-O-sulfate + H2O 77.3% hydrolysis by arylsulfatase ASPC, 100% hydrolysis by arylsulfatase Hp-AS Helix pomatia N-acetyltyramine + sulfate
-
 ?
3.1.6.1 N-[(3a,5b,7b)-7-hydroxy-24-oxo-3-(sulfooxy)cholan-24-yl]-glycine 46.8% hydrolysis by arylsulfatase ASPC Helix pomatia ? + sulfate
-
 ?
3.1.6.1 p-butenylphenol sulfate + H2O 83.5% hydrolysis by arylsulfatase ASPC Helix pomatia p-butenylphenol + sulfate
-
 ?
3.1.6.1 p-coumaric acid sulfate + H2O 70.2% hydrolysis by arylsulfatase ASPC, 100% hydrolysis by arylsulfatase Hp-AS Helix pomatia p-coumaric acid + sulfate
-
 ?
3.1.6.1 p-cresyl sulfate + H2O 100% hydrolysis by arylsulfatase ASPC, 100% hydrolysis by arylsulfatase Hp-AS Helix pomatia p-cresol + sulfate
-
 ?
3.1.6.1 paracetamol sulfate + H2O 96.4% hydrolysis by arylsulfatase ASPC Helix pomatia paracetamol + sulfate
-
 ?
3.1.6.1 phloroglucinol sulfate 98.0% hydrolysis by arylsulfatase ASPC Helix pomatia phloroglucinol + sulfate
-
 ?
3.1.6.1 quinoline-4,8-diol sulfate + H2O 63.0% hydrolysis by arylsulfatase ASPC Helix pomatia quinoline-4,8-diol + sulfate
-
 ?
3.1.6.1 sinapic acid sulfate + H2O 92.2% hydrolysis by arylsulfatase ASPC Helix pomatia sinapic acid + sulfate
-
 ?
3.1.6.1 thymol sulfate + H2O 88.5% hydrolysis by arylsulfatase ASPC Helix pomatia thymol + sulfate
-
 ?
3.1.6.1 vinylphenol sulfate 56.0% hydrolysis by arylsulfatase ASPC Helix pomatia vinylphenol + sulfate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.1.6.1 aspC
-
 Helix pomatia
3.1.6.1 Hp-AS
-
 Helix pomatia