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Literature summary extracted from

  • Vuppada, R.; Hansen, C.; Strickland, K.; Kelly, K.; McCleary, W.
    Phosphate signaling through alternate conformations of the PstSCAB phosphate transporter (2018), BMC Microbiol., 18, 008.
    View publication on PubMed

Protein Variants

EC Number Protein Variants Comment Organism
7.3.2.1 E179Q mutation predicted to lock the PstB protein in either of two conformations. Mutation is predicted to reside in an outward-facing, closed conformation and signals phosphate starvation. Mutant does not show phosphate transport Escherichia coli
7.3.2.1 Q160K mutation predicted to lock the PstB protein in either of two conformations. Mutation is predicted to reside in an inward-facing, open conformation and signals phosphate sufficiency. Mutant does not show phosphate transport Escherichia coli

Organism

EC Number Organism UniProt Comment Textmining
7.3.2.1 Escherichia coli
-
-
-
7.3.2.1 Escherichia coli BW25113
-
-
-

Synonyms

EC Number Synonyms Comment Organism
7.3.2.1 PstSCAB
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
7.3.2.1 metabolism the alternating conformations of the PstSCAB transporter are sensed by PhoR and PhoU. The sensory mechanism controls the alternate autokinase and phospho-PhoB phosphatase activities of PhoR, which ultimately control the signaling state of the response regulator PhoB Escherichia coli