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Literature summary extracted from
- Lytic polysaccharide monooxygenases as chitin-specific virulence factors in crayfish plague (2021), Biomolecules, 11, 1180.
Cloned(Commentary)
| EC Number | Cloned (Comment) | Organism |
|---|---|---|
| 1.14.99.53 | expression in Escherichia coli | Aphanomyces astaci |
Crystallization (Commentary)
| EC Number | Crystallization (Comment) | Organism |
|---|---|---|
| 1.14.99.53 | homology modeling reveals the typical central beta-sandwich fold of LPMOs, as well as flexible loops and two stabilizing disulfide bonds. The active site contains the histidine brace, consisting of His1 and His96 coordinating the copper cofactor, and the axial, non-coordinating residue Phe187 | Aphanomyces astaci |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 1.14.99.53 | copper | His1 and His96 coordinate the copper cofactor | Aphanomyces astaci |  |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 1.14.99.53 | Aphanomyces astaci | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 1.14.99.53 | mycelium | AaAA15A is the most highly expressed AA15-encoding gene in both sporulating and growing mycelia | Aphanomyces astaci | - |
| 1.14.99.53 | zoospore | low expression level of AA15A | Aphanomyces astaci | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 1.14.99.53 | alpha-chitin + gallate + O2 | - |
Aphanomyces astaci | chito-oligosaccharide + C1-aldonic acids + ? + H2O | - |
? | |
| 1.14.99.53 | beta-chitin + gallate + O2 | - |
Aphanomyces astaci | ? + H2O | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 1.14.99.53 | AA15 lytic polysaccharide monooxygenase | - |
Aphanomyces astaci |
| 1.14.99.53 | AA15A | - |
Aphanomyces astaci |
Temperature Stability [°C]
| EC Number | Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 1.14.99.53 | 49.3 | - |
melting temperature, presence of EDTA | Aphanomyces astaci |
| 1.14.99.53 | 59.2 | - |
melting temperature | Aphanomyces astaci |
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