EC Number | Application | Comment | Organism |
---|---|---|---|
1.11.1.8 | analysis | evaluation of a rapid assay for TPO inhibition, using a stable fluorescent product (Amplex UltraRed). The assay consistently identifies the relative potency of strong to moderate inhibitors and chemicals known to be inactive. Results are less consistent for chemicals reported to be weak inhibitors of rodent TPO | Homo sapiens |
EC Number | Cloned (Comment) | Organism |
---|---|---|
1.11.1.8 | expression in CHO and LentiX-293 cell | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.11.1.8 | 2,2',4,4'-tetrahydroxybenzophenone | - |
Homo sapiens | |
1.11.1.8 | 2-mercaptobenzothiazole | - |
Homo sapiens | |
1.11.1.8 | 6-Propyl-2-thiouracil | - |
Homo sapiens | |
1.11.1.8 | amino-1,2,4-triazole | - |
Homo sapiens | |
1.11.1.8 | genistein | - |
Homo sapiens | |
1.11.1.8 | Methimazole | - |
Homo sapiens | |
1.11.1.8 | resorcinol | - |
Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.11.1.8 | Homo sapiens | P07202 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
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