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Literature summary extracted from

  • Selinski, J.; Hartmann, A.; Deckers-Hebestreit, G.; Day, D.; Whelan, J.; Scheibe, R.
    Alternative oxidase isoforms are differentially activated by tricarboxylic acid cycle intermediates (2018), Plant Physiol., 176, 1423-1432 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.10.3.11 2-oxoglutarate activates Arabidopsis thaliana
1.10.3.11 additional information AOX1C is insensitive to: citrate, isocitrate, 2-oxoglutarate, succinate, fumarate, malate, and oxaloacetate Arabidopsis thaliana
1.10.3.11 oxaloacetate activates Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.10.3.11 2 ubiquinol + O2 Arabidopsis thaliana
-
 2 ubiquinone + 2 H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.10.3.11 Arabidopsis thaliana A0A1P8AP13
-
-
1.10.3.11 Arabidopsis thaliana O22048
-
-
1.10.3.11 Arabidopsis thaliana O22049
-
-
1.10.3.11 Arabidopsis thaliana O23913
-
-
1.10.3.11 Arabidopsis thaliana Q39219
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.10.3.11 2 ubiquinol + O2
-
 Arabidopsis thaliana 2 ubiquinone + 2 H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.10.3.11 alternative oxidase
-
 Arabidopsis thaliana
1.10.3.11 AOX1a
-
 Arabidopsis thaliana
1.10.3.11 AOX1b
-
 Arabidopsis thaliana
1.10.3.11 AOX1C
-
 Arabidopsis thaliana
1.10.3.11 AOX1D
-
 Arabidopsis thaliana
1.10.3.11 AOX2
-
 Arabidopsis thaliana

General Information

EC Number General Information Comment Organism
1.10.3.11 metabolism AOX isoforms from Arabidopsis are differentially fine-regulated by tricarboxylic acid cycle metabolites Arabidopsis thaliana
1.10.3.11 metabolism AOX isoforms from Arabidopsis are differentially fine-regulated by tricarboxylic acid cycle metabolites. Expression of isoenzyme AOX1D is increased in aox1a knockout mutants from Arabidopsis (especially after restriction of the cytochrome c pathway) but cannot compensate for the lack of AOX1A, suggesting a difference in the regulation of these isoforms Arabidopsis thaliana