Literature summary extracted from

Banh, R.; Kim, E.; Spillier, Q.; Biancur, D.; Yamamoto, K.; Sohn, A.; Shi, G.; Jones, D.; Kimmelman, A.; Pacold, M.
The polar oxy-metabolome reveals the 4-hydroxymandelate CoQ10 synthesis pathway (2021), Nature, 597, 420-425 .

Metals/Ions

EC Number	Metals/Ions	Comment	Organism	Structure
1.13.11.46	Fe2+	required	Homo sapiens

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
1.13.11.46	4-hydroxyphenylpyruvate + O2	Homo sapiens	-	4-hydroxymandelate + CO2	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
1.13.11.46	Homo sapiens	Q96IR7	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
1.13.11.46	MiaPaCa-2 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1.13.11.46	4-hydroxyphenylpyruvate + O2	-	Homo sapiens	4-hydroxymandelate + CO2	-	?

Subunits

EC Number	Subunits	Comment	Organism
1.13.11.46	?	x * 37000, SDS-PAGE	Homo sapiens

Synonyms

EC Number	Synonyms	Comment	Organism
1.13.11.46	HPDL	-	Homo sapiens
1.13.11.46	hydroxyphenylpyruvate dioxygenase-like	-	Homo sapiens

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Release 2023.1 (January 2023)